Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 1/20 | 0.58 |
| ▸ | ABL1 | P00519 | 4/20 | 0.53 |
| ▸ | BCR | P11274 | 3/20 | 0.53 |
| ▸ | PRKCA | P17252 | 3/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.53 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.53 |
| ▸ | CDK2 | P24941 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | PTK6 | Q13882 | 2/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | SRC | P12931 | 1/20 | 0.52 |
| ▸ | CDK4 | P11802 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.51 |
| ▸ | CDK1 | P06493 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25826396 | 0.85 | HPGD (0.53) | ROCK1ABCG2ABCC1CDK2KMT2A | |
| SCHEMBL25822189 | 0.84 | BRAF (0.70) | KMT2AALDH1A1RAB9AMEN1MAPT | |
| SCHEMBL1460401 | 0.82 | ROCK1 (0.58) | ROCK1ABL1BCRPRKCAABCG2 | |
| SCHEMBL26310123 | 0.82 | ROCK1 (0.58) | ROCK1ABL1BCRPRKCAABCG2 | |
| SCHEMBL394734 | 0.82 | KMT2A (0.67) | ROCK1ABCG2KMT2AALDH1A1RAB9A | |
| SCHEMBL1883622 | 0.81 | ABL1 (0.61) | ROCK1ABL1BCRPRKCAABCG2 | |
| SCHEMBL17364440 | 0.80 | TSHR (0.70) | ABCG2ABCC1KMT2AALDH1A1RAB9A | |
| SCHEMBL9243623 | 0.78 | KMT2A (0.59) | ABCG2ABCC1KMT2AALDH1A1RAB9A | |
| SCHEMBL2285411 | 0.78 | ABL1 (0.69) | ROCK1ABL1BCRPRKCAABCG2 | |
| SCHEMBL26310114 | 0.78 | ROCK1 (0.52) | ROCK1ABL1BCRPRKCAABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295114-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295114-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | ROCK1 1600/4885ABL1 1240/4885BCR 2966/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.