Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MITF | O75030 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | KIF11 | P52732 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26310066 | 0.85 | ROCK1 (0.58) | ROCK1KMT2AMAPTPOLBHTT | |
| SCHEMBL25826336 | 0.82 | TSHR (0.50) | HPGDROCK1KMT2AMAPTPOLB | |
| SCHEMBL3178389 | 0.78 | MAPT (0.71) | HPGDALOX12L3MBTL1ROCK1KMT2A | |
| SCHEMBL18289621 | 0.77 | HPGD (0.83) | HPGDALOX12L3MBTL1ROCK1KMT2A | |
| SCHEMBL18289622 | 0.77 | HPGD (0.83) | HPGDALOX12L3MBTL1ROCK1KMT2A | |
| SCHEMBL395942 | 0.77 | HPGD (0.83) | HPGDALOX12L3MBTL1ROCK1KMT2A | |
| SCHEMBL4957626 | 0.77 | HPGD (0.83) | HPGDALOX12L3MBTL1ROCK1KMT2A | |
| SCHEMBL25826366 | 0.77 | ALDH1A1 (0.44) | HPGDKMT2AMAPTPOLBHTT | |
| SCHEMBL4626757 | 0.76 | HSD17B10 (0.75) | HPGDALOX12L3MBTL1KMT2AMAPT | |
| SCHEMBL2144876 | 0.76 | TSHR (0.50) | KMT2AMAPTHTTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | HPGD 2503/4885ALOX12 1667/4885L3MBTL1 2256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.