Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 10/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 3/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CBFB | Q13951 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23999590 | 0.93 | MAPKAPK2 (0.39) | MAPKAPK2KDRKCNH2 | |
| SCHEMBL23999560 | 0.90 | MAPKAPK2 (0.47) | MAPKAPK2SLC2A1SYKMAPK10KDR | |
| SCHEMBL23999950 | 0.90 | KDR (0.47) | MAPKAPK2SLC2A1SYKMAPK10KDR | |
| SCHEMBL23999765 | 0.87 | AURKA (0.36) | KCNH2 | |
| SCHEMBL23999561 | 0.86 | MAPKAPK2 (0.45) | MAPKAPK2SLC2A1SYKMAPK10KDR | |
| SCHEMBL23999611 | 0.86 | MAPKAPK2 (0.45) | MAPKAPK2KDR | |
| SCHEMBL23999434 | 0.84 | MAPT (0.46) | MAPKAPK2SLC2A1SYKMAPK10KCNH2 | |
| SCHEMBL30180640 | 0.84 | MAPT (0.46) | MAPKAPK2SLC2A1SYKMAPK10KCNH2 | |
| SCHEMBL23999471 | 0.83 | KDR (0.43) | MAPKAPK2KDR | |
| SCHEMBL30180358 | 0.83 | KDR (0.43) | MAPKAPK2KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295114-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295114-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | MAPKAPK2 151/4885SLC2A1 1038/4885SYK 1989/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.