Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 13/20 | 0.45 |
| ▸ | KDR | P35968 | 7/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23999612 | 0.93 | DNMT1 (0.41) | — | |
| SCHEMBL23999590 | 0.92 | MAPKAPK2 (0.39) | MAPKAPK2KDR | |
| SCHEMBL23999766 | 0.90 | MAPKAPK2 (0.38) | MAPKAPK2KDR | |
| SCHEMBL30180416 | 0.89 | KDR (0.50) | MAPKAPK2KDR | |
| SCHEMBL23999678 | 0.89 | KDR (0.50) | MAPKAPK2KDR | |
| SCHEMBL30180462 | 0.87 | KDR (0.50) | MAPKAPK2KDR | |
| SCHEMBL23999940 | 0.87 | KDR (0.50) | MAPKAPK2KDR | |
| SCHEMBL23999946 | 0.86 | KDR (0.49) | MAPKAPK2KDR | |
| SCHEMBL30180344 | 0.86 | KDR (0.49) | MAPKAPK2KDR | |
| SCHEMBL26310316 | 0.86 | MAPKAPK2 (0.44) | MAPKAPK2KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-06-15 | — | — | US | disclosed |
| WO-2023081854-A1 | AKT3 MODULATORS | GEORGIAMUNE LLC (US) | 2023-05-11 | — | — | WO | disclosed |
| WO-2021226519-A1 | AKT3 MODULATORS | GEORGIAMUNE LLC (US) | 2021-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | MAPKAPK2 138/4885KDR 3271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.