Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21261994 | 0.93 | AAK1 (0.37) | AAK1 | |
| SCHEMBL26310600 | 0.83 | DGAT1 (0.32) | AAK1 | |
| SCHEMBL21246816 | 0.82 | AAK1 (0.38) | AAK1 | |
| SCHEMBL30137168 | 0.80 | AAK1 (0.39) | AAK1 | |
| SCHEMBL21246858 | 0.80 | AAK1 (0.39) | AAK1 | |
| SCHEMBL21262029 | 0.74 | AAK1 (0.38) | AAK1 | |
| SCHEMBL26310727 | 0.73 | HTT (0.32) | — | |
| SCHEMBL22569499 | 0.72 | POLB (0.42) | — | |
| SCHEMBL21246698 | 0.71 | DGAT1 (0.33) | AAK1 | |
| SCHEMBL21246868 | 0.71 | DGAT1 (0.35) | AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3728267-B1 | TRICYCLIC INHIBITORS OF THE BCL6 BTB DOMAIN PROTEIN-PROTEIN INTERACTION AND USES THEREOF | ONTARIO INSTITUTE FOR CANCER RES OICR (CA) | 2023-09-13 | — | — | EP | disclosed |