Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 20/20 | 0.48 |
| ▸ | PARP2 | Q9UGN5 | 7/20 | 0.48 |
| ▸ | PARP6 | Q2NL67 | 1/20 | 0.44 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.44 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26314222 | 0.89 | PARP1 (0.51) | PARP1PARP2PARP6PARP3 | |
| SCHEMBL26314224 | 0.89 | PARP1 (0.51) | PARP1PARP2PARP6PARP3 | |
| SCHEMBL26309531 | 0.89 | PARP1 (0.51) | PARP1PARP2PARP6PARP3 | |
| SCHEMBL26310786 | 0.86 | PARP1 (0.61) | PARP1PARP2PARP6TIPARPPARP3 | |
| SCHEMBL26310791 | 0.82 | PARP1 (0.63) | PARP1PARP2PARP6TIPARPPARP3 | |
| SCHEMBL26310798 | 0.81 | PARP1 (0.63) | PARP1PARP2PARP6PARP3 | |
| SCHEMBL26310788 | 0.80 | PARP1 (0.63) | PARP1PARP2PARP6PARP3 | |
| SCHEMBL26310787 | 0.79 | PARP1 (0.64) | PARP1PARP2PARP6TIPARPPARP3 | |
| SCHEMBL26310799 | 0.79 | PARP1 (0.65) | PARP1PARP2PARP6PARP3 | |
| SCHEMBL25093629 | 0.77 | PARP1 (0.76) | PARP1PARP2PARP6TIPARPPARP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023178035-A1 | MULTICYCLIC COMPOUNDS | SLAP PHARMACEUTICALS LLC (US) | 2023-09-21 | — | — | WO | disclosed |