Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 15/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 3/20 | 0.45 |
| ▸ | DRD4 | P21917 | 3/20 | 0.45 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | PARP6 | Q2NL67 | 1/20 | 0.42 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26309531 | 1.00 | PARP1 (0.51) | PARP1KDM4EDRD2DRD4PARP2 | |
| SCHEMBL26314222 | 1.00 | PARP1 (0.51) | PARP1KDM4EDRD2DRD4PARP2 | |
| SCHEMBL26310803 | 0.89 | PARP1 (0.48) | PARP1PARP2PARP6PARP3 | |
| SCHEMBL26314230 | 0.86 | PARP1 (0.62) | PARP1PARP2KCNH2PARP6PARP3 | |
| SCHEMBL26310976 | 0.86 | PARP1 (0.62) | PARP1PARP2KCNH2PARP6PARP3 | |
| SCHEMBL26309532 | 0.86 | PARP1 (0.62) | PARP1PARP2KCNH2PARP6PARP3 | |
| SCHEMBL26309545 | 0.83 | PARP1 (0.59) | PARP1KDM4EPARP2KCNH2PARP6 | |
| SCHEMBL26314384 | 0.83 | PARP1 (0.59) | PARP1KDM4EPARP2KCNH2PARP6 | |
| SCHEMBL26314387 | 0.83 | PARP1 (0.59) | PARP1KDM4EPARP2KCNH2PARP6 | |
| SCHEMBL532570 | 0.82 | PARP1 (0.67) | PARP1KDM4EDRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023178035-A1 | MULTICYCLIC COMPOUNDS | SLAP PHARMACEUTICALS LLC (US) | 2023-09-21 | — | — | WO | disclosed |