Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 13/20 | 0.43 |
| ▸ | BCL6 | P41182 | 15/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 6/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22569530 | 1.00 | FPR2 (0.43) | FPR2BCL6NCOR2 | |
| SCHEMBL30595762 | 1.00 | FPR2 (0.43) | FPR2BCL6NCOR2 | |
| SCHEMBL21262022 | 1.00 | FPR2 (0.43) | FPR2BCL6NCOR2 | |
| SCHEMBL30595766 | 1.00 | FPR2 (0.43) | FPR2BCL6NCOR2 | |
| SCHEMBL21262062 | 0.88 | BCL6 (0.46) | FPR2BCL6NCOR2 | |
| SCHEMBL22578920 | 0.85 | FPR2 (0.47) | FPR2BCL6NCOR2 | |
| SCHEMBL22578856 | 0.85 | FPR2 (0.47) | FPR2BCL6NCOR2 | |
| SCHEMBL21262182 | 0.85 | HRH4 (0.35) | FPR2 | |
| SCHEMBL22569407 | 0.81 | HDAC1 (0.35) | FPR2 | |
| SCHEMBL21262198 | 0.80 | FPR2 (0.40) | FPR2BCL6NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3728267-B1 | TRICYCLIC INHIBITORS OF THE BCL6 BTB DOMAIN PROTEIN-PROTEIN INTERACTION AND USES THEREOF | ONTARIO INSTITUTE FOR CANCER RES OICR (CA) | 2023-09-13 | — | — | EP | disclosed |