Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 7/20 | 0.60 |
| ▸ | DNMT3A | Q9Y6K1 | 5/20 | 0.60 |
| ▸ | USP2 | O75604 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | DNMT3L | Q9UJW3 | 3/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | MYC | P01106 | 1/20 | 0.48 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.48 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.48 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.48 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26314595 | 0.90 | DNMT1 (0.58) | DNMT1DNMT3AUSP2MAPTKMT2A | |
| SCHEMBL24003835 | 0.90 | DNMT1 (0.58) | DNMT1DNMT3AUSP2MAPTKMT2A | |
| SCHEMBL30180382 | 0.89 | DNMT1 (0.72) | DNMT1DNMT3AUSP2MAPTKMT2A | |
| SCHEMBL23261798 | 0.89 | DNMT1 (0.72) | DNMT1DNMT3AUSP2MAPTKMT2A | |
| SCHEMBL23999647 | 0.89 | DNMT1 (0.72) | DNMT1DNMT3AUSP2MAPTKMT2A | |
| SCHEMBL24003982 | 0.88 | DNMT1 (0.66) | DNMT1DNMT3AUSP2MAPTKMT2A | |
| SCHEMBL24006111 | 0.88 | DNMT1 (0.66) | DNMT1DNMT3AUSP2MAPTKMT2A | |
| SCHEMBL24003752 | 0.88 | DNMT1 (0.55) | DNMT1DNMT3AUSP2MAPTKMT2A | |
| SCHEMBL26314544 | 0.86 | USP2 (0.60) | DNMT1DNMT3AUSP2MAPTKMT2A | |
| SCHEMBL26314555 | 0.85 | DNMT1 (0.64) | DNMT1DNMT3AUSP2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295114-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295114-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | DNMT1 4758/4885DNMT3A 4679/4885USP2 3789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.