Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | ESRRA | P11474 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26314564 | 0.92 | KMT2A (0.42) | ALDH1A1SMN1; SMN2KMT2ARAB9ANPC1 | |
| SCHEMBL26194437 | 0.91 | LMNA (0.41) | ALDH1A1SMN1; SMN2KMT2ARAB9ANPC1 | |
| SCHEMBL29436357 | 0.91 | KDM4E (0.38) | ALDH1A1SMN1; SMN2KMT2ARAB9ANPC1 | |
| SCHEMBL17558482 | 0.91 | KDM4E (0.38) | ALDH1A1SMN1; SMN2KMT2ARAB9ANPC1 | |
| SCHEMBL17558480 | 0.91 | KDM4E (0.38) | ALDH1A1SMN1; SMN2KMT2ARAB9ANPC1 | |
| SCHEMBL17542370 | 0.90 | KDM4E (0.41) | ALDH1A1SMN1; SMN2KMT2ARAB9ANPC1 | |
| SCHEMBL17542371 | 0.90 | KDM4E (0.41) | ALDH1A1SMN1; SMN2KMT2ARAB9ANPC1 | |
| SCHEMBL18468872 | 0.89 | KDM4E (0.37) | ALDH1A1SMN1; SMN2KMT2ARAB9ANPC1 | |
| SCHEMBL17542388 | 0.89 | PLA2G4B (0.39) | ALDH1A1SMN1; SMN2KMT2ARAB9ANPC1 | |
| SCHEMBL29456534 | 0.86 | KDM4E (0.41) | ALDH1A1SMN1; SMN2KMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11760736-B2 | Processes and intermediates for preparing MCL1 inhibitors | GILEAD SCIENCES, INC. (US) | 2023-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11760736-B2 | Processes and intermediates for preparing MCL1 inhibitors | MCL1, BAK1, BCL3 | ALDH1A1 2336/4885SMN1; SMN2 1917/4885KMT2A 1090/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.