Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20687589 | 0.87 | GAA (0.43) | TRPV1GAAALDH1A1MAPTHSD17B10 | |
| SCHEMBL760553 | 0.79 | TRPV1 (0.55) | TRPV1GAAALDH1A1MAPTHSD17B10 | |
| SCHEMBL19981077 | 0.77 | HRH3 (0.32) | CYP19A1 | |
| SCHEMBL8258292 | 0.76 | ALDH1A1 (0.62) | TRPV1GAAALDH1A1MAPTHSD17B10 | |
| SCHEMBL16193913 | 0.74 | CYP19A1 (0.39) | TRPV1GAAALDH1A1MAPTHSD17B10 | |
| SCHEMBL13265519 | 0.74 | TRPV1 (0.46) | TRPV1GAAALDH1A1MAPTHSD17B10 | |
| SCHEMBL24956776 | 0.72 | KDM4E (0.35) | TRPV1MAPT | |
| SCHEMBL20272779 | 0.72 | TRPV1 (0.41) | TRPV1GAAALDH1A1MAPTHSD17B10 | |
| SCHEMBL15828681 | 0.71 | CYP19A1 (0.36) | TRPV1GAAALDH1A1CYP19A1 | |
| SCHEMBL20228033 | 0.71 | TRPV1 (0.46) | TRPV1GAAALDH1A1MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230278993-A1 | NOVEL TRICYCLIC AROMATIC HETEROCYCLIC COMPOUND AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND USE THEREOF | SHANGHAI LONGWOOD BIOPHARMACEUTICALS CO., LTD. (CN) | 2023-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230278993-A1 | NOVEL TRICYCLIC AROMATIC HETEROCYCLIC COMPOUND AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND USE THEREOF | PDCD1, CD274, PDCD1LG2 | TRPV1 129/4885GAA 2237/4885ALDH1A1 216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.