SCHEMBL263164

SCHEMBL263164

COC(=C(C)C(=O)O)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.54
CES1 P23141 4/20 0.45
CES2 O00748 3/20 0.45
SRC P12931 1/20 0.44
KMT2A Q03164 3/20 0.43
MAPT P10636 3/20 0.43
KDM4E B2RXH2 2/20 0.43
MEN1 O00255 2/20 0.43
ALDH1A1 P00352 2/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
GLA P06280 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
HPGD P15428 2/20 0.42
GAA P10253 1/20 0.42
ALOX15 P16050 2/20 0.41
CYP3A4 P08684 1/20 0.41
MAPK1 P28482 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1137905 1.00 TSHR (0.54) TSHRCES1CES2SRCKMT2A
SCHEMBL8975525 1.00 TSHR (0.54) TSHRCES1CES2SRCKMT2A
Methacrylic Acid SCHEMBL8425090 0.93 TSHR (0.47) TSHRCES1CES2SRCKMT2A
Methacrylic Acid SCHEMBL8425080 0.93 TSHR (0.47) TSHRCES1CES2SRCKMT2A
SCHEMBL28374366 0.86 TSHR (0.52) TSHRCES1CES2SRCKMT2A
SCHEMBL21197999 0.84 TSHR (0.50) TSHRCES1CES2SRCKMT2A
SCHEMBL998239 0.81 TSHR (0.56) TSHRCES1CES2SRCKMT2A
SCHEMBL6204752 0.80 ELANE (0.52) TSHRCES1CES2KMT2AMAPT
SCHEMBL19991001 0.80 TSHR (0.50) TSHRCES1CES2KMT2AMAPT
SCHEMBL9562937 0.80 ELANE (0.52) TSHRCES1CES2KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2517895-B1 ARTIFICIAL MARBLE HAVING TRANSPARENT AMORPHOUS PATTERN CHEIL IND INC (KR) 2016-02-17 EP claimed
EP-0745621-B1 Polymerisable composition based on thio(meth)acrylate monomer, transparent polymer compositions and their optical use ESSILOR INT (FR) 1998-04-15 EP claimed
EP-0745621-A1 Polymerisable composition based on thio(meth)acrylate monomer, transparent polymer compositions and their optional use ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 1996-12-04 EP claimed
US-10144822-B2 Transparent artificial chips and artificial marble comprising the same LOTTE ADVANCED MATERIALS CO., LTD. (KR) 2018-12-04 US disclosed
EP-1579521-B1 CURABLE COMPOSITION, CURED PRODUCT THEREOF, MOLDED PRODUCT THEREOF AND USE AS FUEL CELL SEPARATOR SHOWA DENKO KK (JP) 2018-04-11 EP disclosed
EP-3233794-A1 INDENYL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND MEDICAL USES THEREOF ADT Pharmaceuticals, Inc. (US) 2017-10-25 EP disclosed
EP-3233071-A1 METHOD OF TREATING OR PREVENTING RAS-MEDIATED DISEASES ADT Pharmaceuticals, Inc. (US) 2017-10-25 EP disclosed
US-9677286-B2 Conductive flooring material and a production method therefor LG HAUSYS, LTD. (KR) 2017-06-13 US disclosed
US-9644078-B2 Release film and method for manufacturing the same LG HAUSYS, LTD. (KR) 2017-05-09 US disclosed
US-9441064-B2 Curable composition, transparent heat-resistant material, and use thereof SHOWA DENKO K.K. (JP) 2016-09-13 US disclosed
WO-2016100542-A1 INDENYL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND MEDICAL USES THEREOF ADT PHARMACEUTICALS, INC. (US) 2016-06-23 WO disclosed
EP-1529087-A1 ADHESIVE MATERIALS HAVING A HIGH REFRACTIVE INDEX BASED ON ACRYLATE BLOCK COPOLYMERS Tesa AG (DE) 2005-05-11 EP disclosed
WO-2004015020-A1 ADHESIVE MATERIALS HAVING A HIGH REFRACTIVE INDEX BASED ON ACRYLATE BLOCK COPOLYMERS TESA AG (DE) 2004-02-19 WO disclosed
EP-0745621-B1 Polymerisable composition based on thio(meth)acrylate monomer, transparent polymer compositions and their optical use ESSILOR INT (FR) 1998-04-15 EP disclosed
WO-1997044312-A9 TWO STEP SYNTHESIS OF D- AND L- α-AMINO ACIDS AND D- AND L- α-AMINO ALDEHYDES 1998-03-12 WO disclosed
WO-1997044312-A1 TWO STEP SYNTHESIS OF D- AND L- α-AMINO ACIDS AND D- AND L- α-AMINO ALDEHYDES THE SCRIPPS RESEARCH INSTITUTE (US) 1997-11-27 WO disclosed
EP-0745620-B1 Polymerisable compositions based on thio(meth)acrylate monomers, polymers having low yellowness index made from these compositions and ophthalmic lenses made therefrom ESSILOR INT (FR) 1997-10-29 EP disclosed
EP-0745621-A1 Polymerisable composition based on thio(meth)acrylate monomer, transparent polymer compositions and their optional use ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 1996-12-04 EP disclosed
EP-0745620-A1 Polymerisable compositions based on thio(meth)acrylate monomers, polymers having low yellowness index made from these compositions and ophthalmic lenses made therefrom ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 1996-12-04 EP disclosed
WO-1991011490-A1 COMPATIBLE POLYARYLACRYLATE AND POLYESTER MIXTURES RÖHM GMBH (DE) 1991-08-08 WO disclosed