SCHEMBL28374366

SCHEMBL28374366

COC(=O)C(C)=C(OC)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.52
CES1 P23141 3/20 0.43
CES2 O00748 2/20 0.43
SRC P12931 1/20 0.43
HPGD P15428 3/20 0.41
GAA P10253 1/20 0.41
KMT2A Q03164 2/20 0.41
MAPT P10636 3/20 0.40
CYP3A4 P08684 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
LMNA P02545 2/20 0.40
ELANE P08246 1/20 0.40
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
ALOX15 P16050 1/20 0.40
MAPK1 P28482 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
F2 P00734 1/20 0.40
POLB P06746 1/20 0.40
RAB9A P51151 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8975525 0.86 TSHR (0.54) TSHRCES1CES2SRCHPGD
SCHEMBL1137905 0.86 TSHR (0.54) TSHRCES1CES2SRCHPGD
SCHEMBL263164 0.86 TSHR (0.54) TSHRCES1CES2SRCHPGD
SCHEMBL14868116 0.83 TSHR (0.56) TSHRCES1CES2SRCHPGD
SCHEMBL15081529 0.83 TSHR (0.56) TSHRCES1CES2SRCHPGD
SCHEMBL14868118 0.83 TSHR (0.56) TSHRCES1CES2SRCHPGD
SCHEMBL8425084 0.83 ELANE (0.46) TSHRCES1CES2SRCHPGD
SCHEMBL21197999 0.82 TSHR (0.50) TSHRCES1CES2SRCHPGD
SCHEMBL1158705 0.82 TSHR (0.54) TSHRCES1CES2SRCHPGD
SCHEMBL2996805 0.82 TSHR (0.54) TSHRCES1CES2SRCHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107674027-B 13C-marked pyraoxystrobin and synthetic method thereof 河南衡谱分析检测技术有限公司 2020-03-27 CN claimed
CN-107674027-B 13C-marked pyraoxystrobin and synthetic method thereof 河南衡谱分析检测技术有限公司 2020-03-27 CN disclosed