Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.45 |
| ▸ | GPR3 | P46089 | 1/20 | 0.44 |
| ▸ | GAK | O14976 | 1/20 | 0.41 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.41 |
| ▸ | COQ8A | Q8NI60 | 1/20 | 0.41 |
| ▸ | NLK | Q9UBE8 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | WDR5 | P61964 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29612165 | 0.81 | POLB (0.57) | POLBKDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL18436063 | 0.79 | MEN1 (0.43) | POLBKDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL31651581 | 0.79 | POLB (0.55) | POLBKDM4EALDH1A1MAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2879864 | 0.79 | POLB (0.55) | POLBKDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL17685059 | 0.77 | POLB (0.52) | POLBKDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL29661797 | 0.75 | CCR1 (0.52) | KDM4EGPR3HRH3CYP1A2 | |
| SCHEMBL3156746 | 0.75 | CCR1 (0.52) | KDM4EGPR3HRH3CYP1A2 | |
| SCHEMBL20178365 | 0.75 | LRRK2 (0.54) | POLBPDPK1GAK | |
| SCHEMBL10337231 | 0.74 | POLB (0.53) | POLBKDM4EALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL28817987 | 0.74 | POLB (0.49) | POLBKDM4EALDH1A1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295114-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295114-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | POLB 2552/4885KDM4E 3961/4885ALDH1A1 4544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.