Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 8/20 | 0.53 |
| ▸ | RAB9A | P51151 | 8/20 | 0.53 |
| ▸ | JAK2 | O60674 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | USP2 | O75604 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21530466 | 0.90 | MCHR1 (0.59) | MCHR1NPC1RAB9AJAK2HTT | |
| SCHEMBL21530447 | 0.86 | NPC1 (0.60) | MCHR1NPC1RAB9AJAK2SMN1; SMN2 | |
| SCHEMBL26317580 | 0.84 | NPC1 (0.56) | MCHR1NPC1RAB9AJAK2SMN1; SMN2 | |
| SCHEMBL21530400 | 0.81 | MCHR1 (0.49) | MCHR1NPC1RAB9AJAK2SMN1; SMN2 | |
| SCHEMBL29621800 | 0.81 | MCHR1 (0.49) | MCHR1NPC1RAB9AJAK2SMN1; SMN2 | |
| SCHEMBL21530417 | 0.81 | RAB9A (0.59) | MCHR1NPC1RAB9AJAK2SMN1; SMN2 | |
| SCHEMBL29621779 | 0.79 | RAB9A (0.65) | MCHR1NPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL21530457 | 0.79 | RAB9A (0.65) | MCHR1NPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL24019187 | 0.79 | NPC1 (0.61) | MCHR1NPC1RAB9AJAK2SMN1; SMN2 | |
| SCHEMBL21530413 | 0.77 | NPC1 (0.54) | MCHR1NPC1RAB9AJAK2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11739072-B2 | Heteroaryl compounds and their use | MINORYX THERAPEUTICS S.L. (ES) | 2023-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11739072-B2 | Heteroaryl compounds and their use | GBA1, GBA2, GAA | MCHR1 1729/4885NPC1 16/4885RAB9A 83/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.