Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRA | P16234 | 4/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.47 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.45 |
| ▸ | GAK | O14976 | 1/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27947745 | 0.81 | MTNR1B (0.50) | PDGFRAPDGFRBPDPK1PDE10AKDM4E | |
| SCHEMBL5221215 | 0.81 | PDE10A (0.48) | PDGFRAPDGFRBPDPK1PDE10APDE3B | |
| SCHEMBL11154928 | 0.79 | DOT1L (0.46) | PDGFRAPDGFRBPDPK1GAKPDE10A | |
| SCHEMBL2203334 | 0.79 | PDPK1 (0.45) | PDGFRAPDGFRBPDPK1GAKPDE10A | |
| SCHEMBL2204145 | 0.79 | EGFR (0.47) | PDPK1GAKPDE10APDE3BPDE3A | |
| SCHEMBL2815588 | 0.79 | PDPK1 (0.45) | PDPK1PDE10APDE3BPDE3AKDM4E | |
| SCHEMBL2200297 | 0.79 | SMN1; SMN2 (0.51) | PDPK1GAKPDE10AKDM4EHPGD | |
| SCHEMBL11727493 | 0.79 | GAK (0.61) | PDGFRAPDGFRBGAKKDRDOT1L | |
| SCHEMBL16132523 | 0.78 | PDGFRB (0.42) | PDGFRAPDGFRBPDPK1GAKPDE10A | |
| SCHEMBL25823870 | 0.77 | MCHR1 (0.41) | GAKPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295114-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295114-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | PDGFRA 1449/4885PDGFRB 996/4885PDPK1 30/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.