Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 17/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | IRAK2 | O43187 | 1/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
| ▸ | CLK2 | P49760 | 1/20 | 0.36 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.36 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | IRAK3 | Q9Y616 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17778098 | 1.00 | IRAK4 (0.43) | IRAK4KDM1AMAOBSMN1; SMN2IRAK2 | |
| SCHEMBL17778137 | 1.00 | IRAK4 (0.43) | IRAK4KDM1AMAOBSMN1; SMN2IRAK2 | |
| SCHEMBL25090988 | 0.85 | HTR4 (0.34) | IRAK4 | |
| SCHEMBL13874224 | 0.82 | KCNH2 (0.36) | — | |
| SCHEMBL3427991 | 0.82 | KCNH2 (0.39) | OPRL1 | |
| Hydrochloric Acid SCHEMBL4167648 | 0.81 | KCNH2 (0.35) | SMN1; SMN2OPRL1 | |
| Hydrochloric Acid SCHEMBL4167653 | 0.81 | KCNH2 (0.35) | SMN1; SMN2OPRL1 | |
| SCHEMBL12793225 | 0.79 | IRAK4 (0.34) | IRAK4 | |
| SCHEMBL27267798 | 0.79 | IRAK4 (0.34) | IRAK4 | |
| SCHEMBL13874716 | 0.79 | KDM1A (0.45) | IRAK4KDM1AMAOBSMN1; SMN2IRAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2560967-B1 | Heterocyclic carboxylic acid amides as PDK1 inihibitors | BOEHRINGER INGELHEIM INT (DE) | 2017-12-20 | — | — | EP | disclosed |
| US-20120094976-A1 | NEW CHEMICAL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120094976-A1 | NEW CHEMICAL COMPOUNDS | CCNB1, MKI67, CCNA1 | IRAK4 3826/4885KDM1A 601/4885MAOB 154/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.