Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL420888 | 1.00 | PTGS1 (0.31) | PTGS1AKR1C3APEX1 | |
| SCHEMBL29740010 | 0.80 | — | — | |
| SCHEMBL2968133 | 0.79 | GRIK1 (0.31) | PTGS1AKR1C3 | |
| SCHEMBL9862266 | 0.79 | PTGS1 (0.30) | PTGS1AKR1C3 | |
| SCHEMBL403113 | 0.79 | PTGS1 (0.30) | PTGS1AKR1C3 | |
| SCHEMBL9820833 | 0.77 | — | — | |
| SCHEMBL8474559 | 0.72 | — | — | |
| SCHEMBL2966908 | 0.72 | — | — | |
| SCHEMBL10707709 | 0.71 | APEX1 (0.32) | APEX1 | |
| SCHEMBL2829521 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090173643-A1 | Packaging Solutions | LAI YU-CHIN | 2009-07-09 | — | — | US | claimed |
| US-20090156708-A1 | BIOMEDICAL DEVICES | SOLTA MEDICAL IRELAND LIMITED (IE) | 2009-06-18 | — | — | US | claimed |
| US-20070254819-A1 | Foaming-resistant hydrocarbon oil compositions | CYTEC SURFACE SPECIALTIES | 2007-11-01 | — | — | US | claimed |
| JP-63159820-A | — | — | None | — | — | JP | disclosed |
| EP-4727985-A2 | TRANSPARENT POLYMERIC MATERIALS WITH HIGH OXYGEN DIFFUSION THAT ARE FREE OF THE ELEMENT FLUORINE | Acuity Polymers, Inc. (US) | 2026-04-22 | — | — | EP | disclosed |
| US-20260103557-A1 | TRANSPARENT POLYMERIC MATERIALS WITH HIGH OXYGEN DIFFUSION THAT ARE FREE OF THE ELEMENT FLUORINE | ACUITY POLYMERS INC (US) | 2026-04-16 | — | — | US | disclosed |
| US-20240425648-A1 | TRANSPARENT POLYMERIC MATERIALS WITH HIGH OXYGEN DIFFUSION THAT ARE FREE OF THE ELEMENT FLUORINE | ACUITY POLYMERS INC (US) | 2024-12-26 | — | — | US | disclosed |
| WO-2024263534-A2 | TRANSPARENT POLYMERIC MATERIALS WITH HIGH OXYGEN DIFFUSION THAT ARE FREE OF THE ELEMENT FLUORINE | ACUITY POLYMERS, INC. (US) | 2024-12-26 | — | — | WO | disclosed |
| WO-2024259430-A1 | TRANSPARENT POLYMERIC MATERIALS WITH HIGH OXYGEN DIFFUSION THAT ARE FREE OF THE ELEMENT FLUORINE | ACUITY POLYMERS, INC. (US) | 2024-12-19 | — | — | WO | disclosed |
| EP-4334328-A1 | TRANSPARENT POLYMERIC MATERIALS WITH HIGH OXYGEN DIFFUSION CONTAINING DI-FUNCTIONAL POSS CAGES WITH HYDROPHILIC SUBSTITUENTS | Acuity Polymers, Inc. (US) | 2024-03-13 | — | — | EP | disclosed |
| US-20220380599-A1 | TRANSPARENT POLYMERIC MATERIALS WITH HIGH OXYGEN DIFFUSION CONTAINING DI-FUNCTIONAL POSS CAGES WITH HYDROPHILIC SUBSTITUENTS | ACUITY POLYMERS, INC. | 2022-12-01 | — | — | US | disclosed |
| US-7261844-B2 | For effectively reducing a period of time for discoloring a contact lens from a colored state to an uncolored state | MENICON CO., LTD. (JP) | 2007-08-28 | — | — | US | disclosed |
| US-20070182918-A1 | METHODS AND SYSTEMS FOR LEACHING SILICONE HYDROGEL OPHTHALMIC LENSES | JOHNSON & JOHNSON VISION CARE, INC. | 2007-08-09 | — | — | US | disclosed |
| US-20070182919-A1 | METHODS AND SYSTEMS FOR LEACHING AND RELEASING SILICONE HYDROGEL OPHTHALMIC LENSES WITH N-HEXANOL SOLUTIONS | JOHNSON & JOHNSON VISISON CARE, INC. | 2007-08-09 | — | — | US | disclosed |
| US-7037954-B2 | Ocular lens material | MENICON CO., LTD. (JP) | 2006-05-02 | — | — | US | disclosed |
| US-20050243273-A1 | Photochromic contact lens having excellent discoloring characteristic | MENICON CO., LTD. (JP) | 2005-11-03 | — | — | US | disclosed |
| US-20050154080-A1 | Contact lenses for extended wear (without surface treatment, coating-free), formed by reacting polyvinylpyrrolidone and (2-methacryloxy-3-hydroxypropyloxy)propylbis(trimethylsiloxy) methylsilane, then curing | JOHNSON & JOHNSON VISION CARE, INC. | 2005-07-14 | — | — | US | disclosed |
| US-5519070-A | FLUORINE, ALKOXY POLYSILOXANE COPOLYMERS FOR INTRAOCULAR LENSES | MENICON CO., LTD. (JP) | 1996-05-21 | — | — | US | disclosed |
| JP-S63159820-A | HARD CONTACT LENS HAVING OXYGEN PERMEABILITY | HOYA CORP | 1988-07-02 | — | — | JP | disclosed |
| US-4112190-A | Metallized plastic molding | MITSUBISHI RAYON CO., LTD. (JP) | 1978-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260103557-A1 | TRANSPARENT POLYMERIC MATERIALS WITH HIGH OXYGEN DIFFUSION THAT ARE FREE OF THE ELEMENT FLUORINE | SMCHD1, ITGB8, POT1 | PTGS1 645/4885AKR1C3 2191/4885APEX1 2494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.