SCHEMBL403113

SCHEMBL403113

CC(=CC(F)C(F)(F)F)C(=O)O

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.30
AKR1C3 P42330 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2829521 0.83
SCHEMBL1482323 0.83 PTGS1 (0.32) PTGS1
SCHEMBL1703519 0.81
SCHEMBL9820833 0.80
SCHEMBL579311 0.79 THRB (0.30)
SCHEMBL312632 0.79 PTGS1 (0.31) PTGS1
SCHEMBL3016142 0.79 APEX1 (0.30)
SCHEMBL420888 0.79 PTGS1 (0.31) PTGS1AKR1C3
SCHEMBL263184 0.79 PTGS1 (0.31) PTGS1AKR1C3
SCHEMBL2326834 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1917857-A Capillary moderator in an osmotic delivery system for preventing backflow into the active agent reservoir ALZA CORP (US) 2007-02-21 CN claimed
US-10591749-B2 Medical device, combination of coating solutions, and method for producing medical device TORAY INDUSTRIES, INC. (JP) 2020-03-17 US disclosed
US-10435515-B2 Both-terminal modified polysiloxane macromonomer and a method for preparing the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2019-10-08 US disclosed
US-10144808-B2 Both-terminal modified polysiloxane macromonomer and a method for preparing the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-12-04 US disclosed
US-20180319940-A1 BOTH-TERMINAL MODIFIED POLYSILOXANE MACROMONOMER AND A METHOD FOR PREPARING THE SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-11-08 US disclosed
EP-2538266-B1 SOFT OCULAR LENS HAVING LOW MOISTURE CONTENT AND METHOD FOR PRODUCING SAME TORAY INDUSTRIES (JP) 2018-08-29 EP disclosed
EP-3290462-A1 BOTH-TERMINAL MODIFIED POLYSILOXANE MACROMONOMER AND A METHOD FOR PREPARING THE SAME Shin-Etsu Chemical Co., Ltd. (JP) 2018-03-07 EP disclosed
US-20180057641-A1 BOTH-TERMINAL MODIFIED POLYSILOXANE MACROMONOMER AND A METHOD FOR PREPARING THE SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-03-01 US disclosed
EP-2745854-B1 MEDICAL DEVICE, AND METHOD FOR PRODUCING SAME TORAY INDUSTRIES (JP) 2018-02-07 EP disclosed
US-9377562-B2 Medical device, and method for producing same TORAY INDUSTRIES, INC. (JP) 2016-06-28 US disclosed
US-20080220245-A1 Transparent Sealing Material For Organic El Device JSR CORPORATION (JP) 2008-09-11 US disclosed
US-20080132666-A1 Fumaric Acid Derivatives and Ophthalmic Lenses Using the Same MENICON NECT CO., LTD. (JP) 2008-06-05 US disclosed
CN-1917857-A Capillary moderator in an osmotic delivery system for preventing backflow into the active agent reservoir ALZA CORP (US) 2007-02-21 CN disclosed
US-7105254-B2 Polymer electrolyte OYAMA NOBORU 2006-09-12 US disclosed
EP-1037294-B1 Polymer electrolyte OYAMA NOBORU (JP) 2005-11-30 EP disclosed
US-20030082458-A1 Polymer electrolyte NOBORU OYAMA (JP) 2003-05-01 US disclosed
US-6509122-B1 Gel copolymer of monomer containing vinyl functionality with diacrylated polyoxyalkylene oligimer or polymer; preventing dendrite formation FUJI JUKOGYO KABUSHIKI KAISHA (JP) 2003-01-21 US disclosed
EP-0876252-B1 USE OF POLYMERS BASED ON ETHYLENE, (METH)ACRYLIC ACID ESTERS AND (METH)ACRYLIC ACID FOR SEALING PANES OF LAMINATED SAFETY GLASS BASF AG (DE) 2002-10-16 EP disclosed
EP-1037294-A2 Polymer electrolyte Oyama, Noboru (JP) 2000-09-20 EP disclosed
US-4904761-A GRAFT COPOLYMER OF A EPOXY RESIN AND VINYL POLYMER HAVING DISPERSED FINE PARTICLES OF SILICONE RUBBER MITSUI TOATSU CHEMICALS, INC. (JP) 1990-02-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080132666-A1 Fumaric Acid Derivatives and Ophthalmic Lenses Using the Same FAH, FH, AQP4 PTGS1 672/4885AKR1C3 56/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.