Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 3/20 | 0.31 |
| ▸ | HTR2C | P28335 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18250270 | 0.84 | MAPK1 (0.34) | MAPK1HTR2AHTR2CALDH1A1IDH1 | |
| SCHEMBL2737250 | 0.78 | IDH1 (0.39) | MAPK1ALDH1A1IDH1 | |
| SCHEMBL24665488 | 0.77 | CNR2 (0.33) | MAPK1ALDH1A1 | |
| SCHEMBL26319285 | 0.77 | MAPK1 (0.36) | MAPK1ALDH1A1 | |
| SCHEMBL21587664 | 0.76 | MAPK1 (0.46) | MAPK1ALDH1A1 | |
| SCHEMBL15077060 | 0.76 | CYP17A1 (0.34) | MAPK1 | |
| SCHEMBL23194583 | 0.75 | — | — | |
| SCHEMBL2737318 | 0.74 | MAPK1 (0.37) | MAPK1ALDH1A1IDH1 | |
| SCHEMBL18250248 | 0.73 | MAPK1 (0.36) | MAPK1HTR2CALDH1A1 | |
| SCHEMBL26319273 | 0.73 | KCNH2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023164057-A1 | DI-CYCLOPROPYL BASED IL-17A MODULATORS AND USES THEREOF | DICE ALPHA, INC. (US) | 2023-08-31 | — | — | WO | disclosed |