Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 4/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25619104 | 0.85 | MAPK1 (0.36) | MAPK1ALDH1A1 | |
| SCHEMBL2737318 | 0.82 | MAPK1 (0.37) | MAPK1ALDH1A1 | |
| SCHEMBL18250248 | 0.81 | MAPK1 (0.36) | MAPK1ALDH1A1 | |
| SCHEMBL25619103 | 0.78 | UBE2M (0.34) | MAPK1 | |
| SCHEMBL25619098 | 0.78 | MPO (0.37) | MAPK1ALDH1A1 | |
| SCHEMBL2737250 | 0.78 | IDH1 (0.39) | MAPK1ALDH1A1 | |
| SCHEMBL26319271 | 0.77 | MAPK1 (0.33) | MAPK1ALDH1A1 | |
| SCHEMBL18250293 | 0.77 | SLC9A1 (0.41) | MAPK1 | |
| SCHEMBL24875216 | 0.76 | MAPK1 (0.34) | MAPK1 | |
| SCHEMBL18250270 | 0.76 | MAPK1 (0.34) | MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023225664-A1 | LACTAM SUBSTITUTED IMIDAZOPYRIDAZINE IL-17A MODULATORS AND USES THEREOF | DICE ALPHA, INC. (US) | 2023-11-23 | — | — | WO | disclosed |
| WO-2023164057-A1 | DI-CYCLOPROPYL BASED IL-17A MODULATORS AND USES THEREOF | DICE ALPHA, INC. (US) | 2023-08-31 | — | — | WO | disclosed |