SCHEMBL26319496

SCHEMBL26319496

N#Cc1ccc([C@H]2CCc3cncn32)c(N)c1

nearest known ligand 0.74

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP11B2 P19099 17/20 0.74
CYP19A1 P11511 8/20 0.74
CYP11B1 P15538 7/20 0.74
KCNH2 Q12809 2/20 0.74
CYP17A1 P05093 1/20 0.74
HRH1 P35367 1/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1039569 1.00 CYP11B2 (0.74) CYP11B2CYP19A1CYP11B1KCNH2CYP17A1
SCHEMBL1039644 0.85 CYP11B2 (1.00) CYP11B2CYP19A1CYP11B1KCNH2CYP17A1
SCHEMBL1041017 0.85 CYP11B2 (1.00) CYP11B2CYP19A1CYP11B1KCNH2CYP17A1
SCHEMBL1039645 0.85 CYP11B2 (1.00) CYP11B2CYP19A1CYP11B1KCNH2CYP17A1
SCHEMBL1041353 0.85 CYP11B2 (1.00) CYP11B2CYP19A1CYP11B1KCNH2CYP17A1
SCHEMBL1039651 0.85 CYP11B2 (1.00) CYP11B2CYP19A1CYP11B1KCNH2CYP17A1
SCHEMBL13015582 0.85 CYP11B2 (0.74) CYP11B2CYP19A1CYP11B1KCNH2CYP17A1
Osilodrostat SCHEMBL1037474 0.85 CYP11B2 (1.00) CYP11B2CYP19A1CYP11B1KCNH2CYP17A1
Osilodrostat SCHEMBL30395982 0.85 CYP11B2 (1.00) CYP11B2CYP19A1CYP11B1KCNH2CYP17A1
Osilodrostat SCHEMBL12460772 0.85 CYP11B2 (1.00) CYP11B2CYP19A1CYP11B1KCNH2CYP17A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230295322-A1 BINDING MOLECULES AGAINST BCMA AND USES THEREOF NOVARTIS AG (CH) 2023-09-21 US disclosed
US-20230295322-A1 BINDING MOLECULES AGAINST BCMA AND USES THEREOF NOVARTIS AG (CH) 2023-09-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230295322-A1 BINDING MOLECULES AGAINST BCMA AND USES THEREOF EPCAM, CD40, BCR CYP11B2 4077/4885CYP19A1 2165/4885CYP11B1 3533/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.