Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 3/20 | 0.37 |
| ▸ | MMP2 | P08253 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | MMP8 | P22894 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.32 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
| ▸ | CPA1 | P15085 | 1/20 | 0.32 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25447596 | 0.83 | HDAC7 (0.38) | ALDH1A1MMP1MMP2CA1CA2 | |
| SCHEMBL22605301 | 0.79 | TSHR (0.39) | ALDH1A1MMP1MMP2MMP3MAPK1 | |
| SCHEMBL4766747 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL21378767 | 0.76 | CA1 (0.44) | ALDH1A1MMP1MMP2CA1CA2 | |
| SCHEMBL20097759 | 0.72 | ALDH1A1 (0.33) | ALDH1A1MAPK1MEN1FAAHKMT2A | |
| SCHEMBL13609165 | 0.72 | TSHR (0.54) | ALDH1A1MMP1MMP2CA1CA2 | |
| SCHEMBL10031629 | 0.72 | ALDH1A1 (0.42) | ALDH1A1MMP1MMP2CA1CA2 | |
| SCHEMBL13876693 | 0.72 | ALDH1A1 (0.42) | ALDH1A1MMP1MMP2CA1CA2 | |
| SCHEMBL2122233 | 0.72 | CA12 (0.42) | ALDH1A1MMP1MMP2CA1CA2 | |
| SCHEMBL24848507 | 0.72 | CA12 (0.42) | ALDH1A1MMP1MMP2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023164057-A1 | DI-CYCLOPROPYL BASED IL-17A MODULATORS AND USES THEREOF | DICE ALPHA, INC. (US) | 2023-08-31 | — | — | WO | disclosed |