Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KDM5A | P29375 | 5/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.39 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | DGKA | P23743 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26319565 | 0.93 | KDM5A (0.51) | TSHRALDH1A1LMNAL3MBTL1KDM5A | |
| SCHEMBL17451524 | 0.90 | TSHR (0.61) | TSHRALDH1A1LMNAL3MBTL1KMT2A | |
| SCHEMBL64678 | 0.84 | KMT2A (0.54) | TSHRALDH1A1LMNAL3MBTL1KMT2A | |
| SCHEMBL64222 | 0.84 | KMT2A (0.54) | TSHRALDH1A1LMNAL3MBTL1KMT2A | |
| SCHEMBL28399246 | 0.83 | KDM5A (0.58) | TSHRALDH1A1LMNAL3MBTL1KDM5A | |
| SCHEMBL11800393 | 0.83 | KDM5A (0.54) | TSHRALDH1A1LMNAL3MBTL1KDM5A | |
| SCHEMBL28399964 | 0.83 | KDM5A (0.58) | TSHRALDH1A1LMNAL3MBTL1KDM5A | |
| SCHEMBL8377126 | 0.83 | TSHR (0.52) | TSHRALDH1A1LMNAL3MBTL1KMT2A | |
| SCHEMBL13903730 | 0.83 | KDM5A (0.58) | TSHRALDH1A1LMNAL3MBTL1KDM5A | |
| Hexadecanoic Acid Methyl Ester SCHEMBL28398014 | 0.83 | KDM5A (0.58) | TSHRALDH1A1LMNAL3MBTL1KDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230270685-A1 | POLYNUCLEOTIDES ENCODING METHYLMALONYL-CoA MUTASE | MODERNATX, INC. (US) | 2023-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230270685-A1 | POLYNUCLEOTIDES ENCODING METHYLMALONYL-CoA MUTASE | POLM, EMG1, MCM6 | TSHR 4804/4885ALDH1A1 3153/4885LMNA 594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.