Sugi Predict
/ Targets
/ MCM6
Top predicted compounds (top 20 by supporting neighbours, then confidence)
| Compound | Confidence | Supporting neighbours |
|---|
Clinical trials — most relevant to MCM6 by text similarity (a relevance ranking, not an exhaustive list)
| Trial | Phase | Status |
|---|
| Clinical and Pharmacoeconomic Assessment of CDK4/6 Inhibitors for Treatment of Breast Cancer in Egypt |
PHASE4 | COMPLETED |
| Cornelia De Lange Syndrome: Assessing Positive Effects of Lithium Treatment |
PHASE2/PHASE3 | RECRUITING |
| TQB3616 Capsules Combined With Abiraterone Acetate Plus Prednisone in Metastatic Castration-Resistant Prostate Cancer |
PHASE2 | UNKNOWN |
| A Phase 1/2 Trial of SRA737 in Subjects With Advanced Cancer |
PHASE1/PHASE2 | COMPLETED |
| Trial of Topotecan With VX-970 (M6620), an ATR Kinase Inhibitor, in Small Cell Cancers and Extrapulmonary Small Cell Cancers |
PHASE1/PHASE2 | COMPLETED |
| A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies |
PHASE1/PHASE2 | RECRUITING |
| Palbociclib and Sasanlimab for the Treatment of Advanced Clear Cell Renal Cell Carcinoma (ccRCC) or Papillary Renal Cell Carcinoma (pRCC) |
PHASE1/PHASE2 | RECRUITING |
| Everolimus in CDK12-Deficient Metastatic Colorectal Cancer (EVER-RECODE) |
PHASE1/PHASE2 | NOT_YET_RECRUITING |
| M7824 and Topotecan or Temozolomide in Relapsed Small Cell Lung Cancers |
PHASE1/PHASE2 | COMPLETED |
| Safety and Efficacy of BMS-986504 in Unresectable Malignant Peripheral Nerve Sheath Tumor |
PHASE1/PHASE2 | NOT_YET_RECRUITING |
| A Pilot Study of the Combination of Retinoic Acid and Interferon-Alpha2a for the Treatment of Lymphoproliferative Disorders in Children With Immunodeficiency Syndromes |
PHASE2 | COMPLETED |
| Open-Label, Randomised, Multi-Drug, Biomarker-Directed, Phase 1b Study in Pts w/ Muscle Invasive Bladder Cancer |
PHASE1 | ACTIVE_NOT_RECRUITING |
| Veliparib (ABT-888), an Oral PARP Inhibitor, and VX-970, an ATR Inhibitor, in Combination With Cisplatin in People With Refractory Solid Tumors |
PHASE1 | COMPLETED |
| Nucleoside Therapy in Patients With Telomere Biology Disorders |
PHASE1 | RECRUITING |
| Plasma Triglyceride Lipolysis in Multifactorial Chylomicronemia |
nan | COMPLETED |
| Role of Geminin and Mcm-2 in Prognosis of Renal Cell Carcinoma |
nan | UNKNOWN |
| Effect of Adenovirus E1A Oncogene on DNA Replication Dynamics |
nan | UNKNOWN |
| Molecular Genetics Study of Nasopharyngeal Carcinoma: Characterization of NCP Susceptibility Gene(s) |
nan | COMPLETED |
| Inherited Genetic Susceptibility in Langerhans Cell Histiocytosis (LCH) |
nan | ACTIVE_NOT_RECRUITING |
| A Proof of Concept Study for the DNA Repair Driven by the Mesenchymal Stem Cells in Critical COVID-19 Patients |
nan | COMPLETED |
| Prospective Validation of a DNA Damage Repair-Hippo Pathway Signature in Patients With Advanced Gastric Cancer |
nan | UNKNOWN |
| Germline Alterations of Tumor Susceptibility Genes in New York Cancer Patients |
nan | ACTIVE_NOT_RECRUITING |
| Identification of Genetic Factors Implicated in Orofacial Cleft Using Whole Exome Sequencing |
nan | RECRUITING |
| Study of the Effect of Innate on the Inflammatory Response to Endotoxin |
nan | RECRUITING |
| Whole Genome Scan of Extended Families With Familial Vocal Cord Paralysis |
nan | COMPLETED |
| Telomeres Length in Israeli Fibrotic ILD Patients |
nan | ENROLLING_BY_INVITATION |
| Small Bowel Capsule Endoscopy in Lynch Syndrome |
nan | RECRUITING |
| Screening for Early Diagnosis of Nose Cancer |
nan | RECRUITING |
| Better Delineation of CDK13 Related Phenotype and Epigenetic Signature. |
nan | UNKNOWN |
| Plant Extracted Natural Compounds Impact on Stage IV Breast Cancer Survival Time and Remission. |
nan | UNKNOWN |
Related proteins — ESM-2 sequence neighbours (a MCM6 binder may also engage these)