SCHEMBL26319768

SCHEMBL26319768

CC1(C)O[C@@H]2C(CO)O[C@@](C#N)(c3ccc4c(N)ncnn34)[C@@H]2O1

nearest known ligand 0.51

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ TMPRSS2 O15393 1/20 0.44
▸ PI4KA P42356 1/20 0.37
▸ PI4K2B Q8TCG2 1/20 0.37
▸ PI4K2A Q9BTU6 1/20 0.37
▸ PI4KB Q9UBF8 1/20 0.37
▸ ADORA2A P29274 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12393281 1.00 TMPRSS2 (0.44) TMPRSS2PI4KAPI4K2BPI4K2API4KB
SCHEMBL22142989 1.00 TMPRSS2 (0.44) TMPRSS2PI4KAPI4K2BPI4K2API4KB
SCHEMBL18605972 1.00 TMPRSS2 (0.44) TMPRSS2PI4KAPI4K2BPI4K2API4KB
SCHEMBL26878544 1.00 TMPRSS2 (0.44) TMPRSS2PI4KAPI4K2BPI4K2API4KB
SCHEMBL26326095 1.00 TMPRSS2 (0.44) TMPRSS2PI4KAPI4K2BPI4K2API4KB
SCHEMBL30418526 1.00 TMPRSS2 (0.44) TMPRSS2PI4KAPI4K2BPI4K2API4KB
SCHEMBL30921711 0.92 TMPRSS2 (0.39) TMPRSS2PI4KAPI4K2BPI4K2API4KB
SCHEMBL30939869 0.92 TMPRSS2 (0.39) TMPRSS2PI4KAPI4K2BPI4K2API4KB
SCHEMBL25909437 0.91 TMPRSS2 (0.37) TMPRSS2
SCHEMBL12393441 0.89 TMPRSS2 (0.42) TMPRSS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080069-A Phospholipid compounds and uses thereof — 2026-05-26 — — CN disclosed
CN-113549120-B Method for preparing ribonucleoside 吉利德科学公司 2025-04-29 — — CN disclosed
CN-108348526-B Methods of treating arenaviridae and coronaviridae viral infections 吉利德科学公司 2025-04-25 — — CN disclosed
CN-119661537-A Nucleoside compound, preparation method thereof, composition thereof and application of nucleoside compound in medicine 中国科学院上海药物研究所 2025-03-21 — — CN disclosed
CN-118994170-A Process for preparing 1' -cyanonucleosides 吉利德科学公司 2024-11-22 — — CN disclosed
CN-118812607-A Method for preparing ribonucleoside 吉利德科学公司 2024-10-22 — — CN disclosed
CN-118786128-A Compounds and methods for treating viral infections 吉利德科学公司 2024-10-15 — — CN disclosed
CN-113620992-B Methods of treating infection by a virus of the family filoviridae 吉利德科学公司 2024-09-03 — — CN disclosed
CN-115298181-B Process for preparing 1' -cyanonucleosides 吉利德科学公司 2024-08-16 — — CN disclosed
CN-118165034-A Nucleotide compound, composition and application thereof 深圳市塔吉瑞生物医药有限公司 2024-06-11 — — CN disclosed
CN-118139868-A Orally bioavailable nucleoside analogs 维纳拓尔斯制药公司 2024-06-04 — — CN disclosed
US-11780844-B2 Compounds and methods for treatment of viral infections GILEAD SCIENCES, INC. (US) 2023-10-10 — — US disclosed
US-20230279013-A1 COMPOUNDS AND METHODS FOR TREATMENT OF VIRAL INFECTIONS GILEAD SCIENCES, INC. 2023-09-07 — — US disclosed
CN-115703796-A Preparation method of important intermediate of Reidesciclovir 苏州恩泰新材料科技有限公司 2023-02-17 — — CN disclosed
CN-115298181-A Process for preparing 1' -cyanonucleosides 吉利德科学公司 2022-11-04 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11780844-B2 Compounds and methods for treatment of viral infections HAVCR2, EIF2AK2, OAT TMPRSS2 112/4885PI4KA 4317/4885PI4K2B 4583/4885
US-20230279013-A1 COMPOUNDS AND METHODS FOR TREATMENT OF VIRAL INFECTIONS HAVCR2, EIF2AK2, OAT TMPRSS2 112/4885PI4KA 4317/4885PI4K2B 4583/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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