Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
| ▸ | PI4KA | P42356 | 1/20 | 0.45 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.45 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.45 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | P2RY6 | Q15077 | 5/20 | 0.43 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.43 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CDA | P32320 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20668803 | 1.00 | LMNA (0.46) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL24829322 | 1.00 | LMNA (0.46) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL25631417 | 0.86 | P2RY6 (0.44) | ALDH1A1P2RY6P2RY2P2RY4 | |
| SCHEMBL24828996 | 0.86 | P2RY6 (0.44) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL24828995 | 0.86 | P2RY6 (0.44) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL20668747 | 0.85 | P2RY6 (0.39) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL24829080 | 0.85 | P2RY6 (0.45) | ALDH1A1P2RY6P2RY2P2RY4 | |
| SCHEMBL24829031 | 0.85 | P2RY6 (0.45) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL20668731 | 0.84 | LMNA (0.63) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL13003005 | 0.84 | LMNA (0.63) | LMNATHRBMTORMDM2NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230293566-A1 | N4-Hydroxycytidine and Derivatives and Anti-Viral Uses Related Thereto | EMORY UNIVERSITY | 2023-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230293566-A1 | N4-Hydroxycytidine and Derivatives and Anti-Viral Uses Related Thereto | TYMP, ADA, CDA | LMNA 1415/4885THRB 4785/4885MTOR 3720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.