Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.51 |
| ▸ | BCR | P11274 | 2/20 | 0.51 |
| ▸ | ABL2 | P42684 | 1/20 | 0.51 |
| ▸ | DNMT1 | P26358 | 3/20 | 0.48 |
| ▸ | DNMT3L | Q9UJW3 | 3/20 | 0.48 |
| ▸ | DNMT3A | Q9Y6K1 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 6/20 | 0.46 |
| ▸ | KCNK9 | Q9NPC2 | 5/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30232750 | 0.89 | POLB (0.55) | ABL1BCRABL2DNMT1DNMT3L | |
| SCHEMBL24006110 | 0.89 | POLB (0.55) | ABL1BCRABL2DNMT1DNMT3L | |
| SCHEMBL30287677 | 0.89 | POLB (0.55) | ABL1BCRABL2DNMT1DNMT3L | |
| SCHEMBL24003919 | 0.89 | POLB (0.55) | ABL1BCRABL2DNMT1DNMT3L | |
| SCHEMBL30290811 | 0.87 | KCNK3 (0.53) | DNMT1DNMT3LDNMT3APOLBMEN1 | |
| SCHEMBL24010669 | 0.87 | KCNK3 (0.53) | DNMT1DNMT3LDNMT3APOLBMEN1 | |
| SCHEMBL24004057 | 0.84 | ABL1 (0.57) | ABL1BCRABL2DNMT1DNMT3L | |
| SCHEMBL1890995 | 0.82 | DNMT1 (0.73) | ABL1BCRABL2DNMT1DNMT3L | |
| SCHEMBL26321800 | 0.81 | ABL1 (0.59) | ABL1BCRABL2DNMT1POLB | |
| SCHEMBL13335899 | 0.80 | KCNK3 (0.67) | POLBMAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295114-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295114-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | ABL1 1240/4885BCR 2966/4885ABL2 1973/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.