Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.71 |
| ▸ | F2 | P00734 | 1/20 | 0.61 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.61 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.61 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.61 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | ABL1 | P00519 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | IDE | P14735 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | HLCS | P50747 | 3/20 | 0.60 |
| ▸ | PLCD1 | P51178 | 1/20 | 0.60 |
| ▸ | CA12 | O43570 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14614382 | 1.00 | TDP1 (0.71) | TDP1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL22473615 | 0.95 | TDP1 (0.68) | TDP1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL31677482 | 0.94 | TDP1 (0.66) | TDP1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL10051079 | 0.94 | TDP1 (0.70) | TDP1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL13899175 | 0.94 | TDP1 (0.70) | TDP1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL23126169 | 0.94 | TDP1 (0.70) | TDP1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL19034459 | 0.94 | TDP1 (0.70) | TDP1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL23126156 | 0.94 | TDP1 (0.70) | TDP1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8650557 | 0.94 | TDP1 (0.70) | TDP1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL18779801 | 0.94 | TDP1 (0.78) | TDP1F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120100077-A1 | MIXTURE OF AMPHIPATHIC MOLECULES AND METHOD FOR MODIFYING CELL MEMBRANES BY MEANS OF FUSION | FORSCHUNGSZENTRUM JUELICH GMBH (DE) | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120100077-A1 | MIXTURE OF AMPHIPATHIC MOLECULES AND METHOD FOR MODIFYING CELL MEMBRANES BY MEANS OF FUSION | ANXA2, DNM2, ANXA6 | TDP1 3861/4885F2 2115/4885PRSS1 3071/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.