Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 4/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24003947 | 0.80 | CYP11B2 (0.46) | CYP11B2CYP11B1CYP2D6NPC1RAB9A | |
| SCHEMBL24003929 | 0.78 | CYP11B2 (0.39) | CYP11B2CYP11B1NPC1RAB9APIK3CG | |
| SCHEMBL25827086 | 0.77 | CYP11B2 (0.39) | CYP11B2CYP11B1NPC1RAB9AFFAR4 | |
| SCHEMBL26322920 | 0.77 | MAPK14 (0.53) | CYP11B2CYP11B1CYP2D6NPC1RAB9A | |
| SCHEMBL29985044 | 0.77 | UGCG (0.43) | CYP11B2CYP11B1NPC1RAB9AFFAR4 | |
| SCHEMBL26328176 | 0.76 | CYP11B2 (0.37) | CYP11B2CYP11B1NPC1RAB9AMAPT | |
| SCHEMBL14259445 | 0.76 | NPC1 (0.67) | CYP11B2CYP11B1CYP2D6NPC1RAB9A | |
| SCHEMBL25820789 | 0.74 | NPC1 (0.41) | CYP11B2CYP11B1CYP2D6NPC1RAB9A | |
| SCHEMBL19967147 | 0.74 | CYP11B2 (0.58) | CYP11B2CYP11B1NPC1RAB9AFFAR4 | |
| SCHEMBL24010356 | 0.72 | MAPK13 (0.38) | CYP11B2NPC1RAB9AGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295114-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295114-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | CYP11B2 860/4885CYP11B1 751/4885CYP2D6 3871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.