Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 4/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | FABP7 | O15540 | 2/20 | 0.47 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.47 |
| ▸ | MDM4 | O15151 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6673820 | 0.87 | KMT2A (0.64) | KMT2AEPHX2CASP3CA1CA2 | |
| SCHEMBL21332462 | 0.82 | KMT2A (0.66) | KMT2AEPHX2CASP3CA1CA2 | |
| SCHEMBL30238049 | 0.81 | KMT2A (0.64) | KMT2AEPHX2CASP3CA1CA2 | |
| SCHEMBL1800381 | 0.81 | KMT2A (0.64) | KMT2AEPHX2CASP3CA1CA2 | |
| SCHEMBL13613350 | 0.80 | KMT2A (0.72) | KMT2AEPHX2CASP3CA1CA2 | |
| SCHEMBL3757636 | 0.80 | KMT2A (0.72) | KMT2AEPHX2CASP3CA1CA2 | |
| SCHEMBL402111 | 0.80 | KMT2A (0.68) | KMT2AEPHX2CASP3CA1CA2 | |
| SCHEMBL29839653 | 0.80 | KMT2A (0.53) | KMT2AEPHX2CASP3CA1CA2 | |
| SCHEMBL12866016 | 0.80 | KMT2A (0.62) | KMT2AEPHX2CASP3CA1CA2 | |
| SCHEMBL31031957 | 0.80 | KMT2A (0.67) | KMT2AEPHX2CASP3CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120101257-A1 | PROCESSES FOR PREPARING AMINO-SUBSTITUTED GAMMA-LACTAMS | UNIVERSITE DE MONTREAL (CA) | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101257-A1 | PROCESSES FOR PREPARING AMINO-SUBSTITUTED GAMMA-LACTAMS | QPCT, GLUL, ASNS | KMT2A 4277/4885EPHX2 4414/4885CASP3 4203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.