⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL178393 | 0.75 | — | — | |
| SCHEMBL15934501 | 0.72 | — | — | |
| SCHEMBL18417203 | 0.72 | — | — | |
| SCHEMBL1285412 | 0.72 | — | — | |
| SCHEMBL24497085 | 0.71 | — | — | |
| SCHEMBL13955232 | 0.71 | — | — | |
| SCHEMBL13936325 | 0.71 | — | — | |
| SCHEMBL19546609 | 0.71 | — | — | |
| SCHEMBL6274547 | 0.69 | KISS1R (0.33) | — | |
| SCHEMBL24497309 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295614-A1 | METHODS AND COMPOSITIONS FOR THE ADAR-MEDIATED EDITING OF ARGININOSUCCINATE LYASE (ASL) | KORRO BIO, INC. | 2023-09-21 | — | — | US | disclosed |