Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 2/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2439457 | 0.92 | MAPT (0.56) | MAPTALDH1A1L3MBTL1MAPK1KDM4E | |
| SCHEMBL27302185 | 0.91 | HSP90AA1 (0.49) | MAPTALDH1A1L3MBTL1MAPK1KDM4E | |
| SCHEMBL28595923 | 0.90 | EPHX2 (0.57) | MAPTALDH1A1L3MBTL1MAPK1KDM4E | |
| SCHEMBL7094216 | 0.90 | EPHX2 (0.57) | MAPTALDH1A1L3MBTL1MAPK1KDM4E | |
| Hydrochloric Acid SCHEMBL27778609 | 0.90 | MAPT (0.54) | MAPTALDH1A1L3MBTL1MAPK1KDM4E | |
| SCHEMBL1278317 | 0.90 | EPHX2 (0.57) | MAPTALDH1A1L3MBTL1MAPK1KDM4E | |
| SCHEMBL2438485 | 0.90 | EPHX2 (0.57) | MAPTALDH1A1L3MBTL1MAPK1KDM4E | |
| SCHEMBL10943919 | 0.88 | CYP2C9 (0.48) | MAPTALDH1A1L3MBTL1 | |
| SCHEMBL13655405 | 0.88 | ALDH1A1 (0.49) | MAPTALDH1A1L3MBTL1KMT2AHTR2A | |
| SCHEMBL10943921 | 0.88 | CYP2C9 (0.48) | MAPTALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0030514-B1 | ANILINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM FOR REGULATING PLANT-GROWTH | RHONE-POULENC AGROCHIMIE (FR) | 1983-08-17 | — | — | EP | claimed |
| EP-0030514-A1 | Aniline derivatives, process for their preparation and compositions containing them for regulating plant-growth | RHONE-POULENC AGROCHIMIE (FR) | 1981-06-17 | — | — | EP | claimed |
| CN-121586705-A | Small molecule prostaglandin F receptor antagonists | 辉凌公司 | 2026-02-27 | — | — | CN | disclosed |
| US-20250099478-A1 | PLASMA KALLIKREIN INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2025-03-27 | — | — | US | disclosed |
| WO-2025021913-A1 | SMALL MOLECULE PROSTAGLANDIN F RECEPTOR ANTAGONISTS | FERRING B.V. (NL) | 2025-01-30 | — | — | WO | disclosed |
| EP-4469458-A1 | PLASMA KALLIKREIN INHIBITORS | Merck Sharp & Dohme LLC (US) | 2024-12-04 | — | — | EP | disclosed |
| CN-118613483-A | Plasma kallikrein inhibitors | 默沙东有限责任公司 | 2024-09-06 | — | — | CN | disclosed |
| WO-2023146809-A9 | PLASMA KALLIKREIN INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2024-03-14 | — | — | WO | disclosed |
| WO-2023146809-A1 | PLASMA KALLIKREIN INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2023-08-03 | — | — | WO | disclosed |
| EP-3285581-B1 | PYRAZOLYL PYRIMIDINONE COMPOUNDS AS PDE2 INHIBITORS | MERCK SHARP & DOHME (US) | 2021-08-11 | — | — | EP | disclosed |
| CN-110724154-B | Polysubstituted pyrrolo [3,4-d ] isoxazole derivative and synthetic method thereof | 湖北科技学院 | 2020-08-04 | — | — | CN | disclosed |
| US-5756529-A | ANTIINFLAMMATORY | G.D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |
| CN-1035552-C | branched alkylamino derivatives of thiazoles, process for their preparation and pharmaceutical compositions containing them | SANOFI ELF (FR) | 1997-08-06 | — | — | CN | disclosed |
| WO-1997011704-A1 | SUBSTITUTED PYRAZOLYL BENZENESULFONAMIDES FOR USE IN VETERINARY THERAPIES AS ANTIINFLAMMATORY AGENTS | G.D. SEARLE & CO. (US) | 1997-04-03 | — | — | WO | disclosed |
| EP-0731795-A1 | SUBSTITUTED PYRAZOLYL BENZENESULFONAMIDES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-09-18 | — | — | EP | disclosed |
| US-5464847-A | Moduators of corticotropin releasing factor | ELF SANOFI (FR) | 1995-11-07 | — | — | US | disclosed |
| WO-1995015316-A1 | SUBSTITUTED PYRAZOLYL BENZENESULFONAMIDES FOR THE TREATMENT OF INFLAMMATION | G. D. SEARLE & CO. (US) | 1995-06-08 | — | — | WO | disclosed |
| CN-1085898-A | branched alkylamino derivatives of thiazoles, process for their preparation and pharmaceutical compositions containing them | SANOFI ELF (FR) | 1994-04-27 | — | — | CN | disclosed |
| EP-0030514-B1 | ANILINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM FOR REGULATING PLANT-GROWTH | RHONE-POULENC AGROCHIMIE (FR) | 1983-08-17 | — | — | EP | disclosed |
| EP-0030514-A1 | Aniline derivatives, process for their preparation and compositions containing them for regulating plant-growth | RHONE-POULENC AGROCHIMIE (FR) | 1981-06-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250099478-A1 | PLASMA KALLIKREIN INHIBITORS | KLKB1, SERPINE1, KLK5 | MAPT 726/4885ALDH1A1 1597/4885L3MBTL1 4286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.