Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 19/20 | 0.50 |
| ▸ | CCNK | O75909 | 19/20 | 0.50 |
| ▸ | CDK9 | P50750 | 19/20 | 0.50 |
| ▸ | CDK12 | Q9NYV4 | 19/20 | 0.50 |
| ▸ | CDK7 | P50613 | 6/20 | 0.50 |
| ▸ | CCNH | P51946 | 6/20 | 0.50 |
| ▸ | MNAT1 | P51948 | 3/20 | 0.50 |
| ▸ | CCNE1 | P24864 | 18/20 | 0.49 |
| ▸ | CDK2 | P24941 | 18/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25595033 | 1.00 | CCNT1 (0.50) | CCNT1CCNKCDK9CDK12CDK7 | |
| SCHEMBL26324656 | 1.00 | CCNT1 (0.50) | CCNT1CCNKCDK9CDK12CDK7 | |
| SCHEMBL26324666 | 1.00 | CCNT1 (0.50) | CCNT1CCNKCDK9CDK12CDK7 | |
| SCHEMBL25595069 | 1.00 | CCNT1 (0.50) | CCNT1CCNKCDK9CDK12CDK7 | |
| SCHEMBL26325033 | 0.96 | CCNK (0.48) | CCNT1CCNKCDK9CDK12CDK7 | |
| SCHEMBL26325032 | 0.96 | CCNK (0.48) | CCNT1CCNKCDK9CDK12CDK7 | |
| SCHEMBL26325089 | 0.96 | CCNK (0.48) | CCNT1CCNKCDK9CDK12CDK7 | |
| SCHEMBL26325034 | 0.96 | CCNK (0.48) | CCNT1CCNKCDK9CDK12CDK7 | |
| SCHEMBL25591498 | 0.92 | CCNK (0.51) | CCNT1CCNKCDK9CDK12CDK7 | |
| SCHEMBL25595165 | 0.92 | CCNK (0.51) | CCNT1CCNKCDK9CDK12CDK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295130-A1 | COMPOUND USEFUL AS CDK7 KINASE INHIBITOR AND USE THEREOF | TYK MEDICINES, INC. (CN) | 2023-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295130-A1 | COMPOUND USEFUL AS CDK7 KINASE INHIBITOR AND USE THEREOF | CDK7, CDK6, CDK9 | CCNT1 42/4885CCNK 15/4885CDK9 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.