SCHEMBL26325418

SCHEMBL26325418

c1cc(-c2ccc(-c3ccc(-c4cc5sc(-c6ccc(-c7ccc(-c8ccncc8)cc7)cc6)cc5s4)cc3)cc2)ccn1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.50
LMNA P02545 1/20 0.50
PDE3B Q13370 3/20 0.46
PDE3A Q14432 3/20 0.46
PIK3CD O00329 2/20 0.46
PIK3CA P42336 2/20 0.46
PIK3CB P42338 2/20 0.46
PIK3CG P48736 2/20 0.46
PIP5K1C O60331 1/20 0.46
PI4KA P42356 1/20 0.46
PI4KB Q9UBF8 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.45
CDC7 O00311 6/20 0.44
DBF4 Q9UBU7 6/20 0.44
QDPR P09417 1/20 0.43
NOTUM Q6P988 1/20 0.42
KIF11 P52732 2/20 0.41
KDM4E B2RXH2 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29176245 0.95 MAPT (0.48) MAPTLMNAPDE3BPDE3APIK3CD
SCHEMBL30099060 0.85 ESR1 (0.47) MAPTLMNAPDE3BPDE3APIK3CD
SCHEMBL20804570 0.80 CDC7 (0.50) MAPTLMNAPDE3BPDE3APIK3CD
SCHEMBL26325426 0.78 CYP2A6 (0.56) PIK3CDPIK3CAPIP5K1CPI4KAPI4KB
SCHEMBL23263983 0.77 GSK3B (0.43) MAPTLMNAPDE3BPDE3APIK3CD
SCHEMBL12562762 0.76 ESR1 (0.52) MAPTLMNAPIK3CAPI4KAPI4KB
SCHEMBL1105093 0.76 ESR1 (0.52) MAPTLMNAPIK3CAPI4KAPI4KB
SCHEMBL31227321 0.75 CYP2A6 (0.51) CDC7DBF4ROCK1CDK2GSK3B
SCHEMBL31227630 0.75 CYP2A6 (0.51) CDC7DBF4
SCHEMBL12562800 0.74 IKBKB (0.46) MAPTSMN1; SMN2KDM4ECYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11770974-B2 P active materials for organic photoelectric conversion layers in organic photodiodes SONY CORPORATION (JP) 2023-09-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11770974-B2 P active materials for organic photoelectric conversion layers in organic photodiodes JUP, L1CAM, EPCAM MAPT 1030/4885LMNA 720/4885PDE3B 2658/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.