Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.61 |
| ▸ | PPARA | Q07869 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 6/20 | 0.44 |
| ▸ | CA2 | P00918 | 5/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5129198 | 0.82 | CA1 (0.61) | CA1PPARACA12CA2CA14 | |
| SCHEMBL15013851 | 0.81 | CA1 (0.35) | CA1CA12CA2CA14CA7 | |
| SCHEMBL9651043 | 0.77 | CA1 (1.00) | CA1PPARACA12CA2CA14 | |
| SCHEMBL27412101 | 0.77 | CA12 (0.40) | CA1CA12CA14CA7CA9 | |
| SCHEMBL25537111 | 0.75 | CA12 (0.35) | CA1CA12CA2CA14CA7 | |
| SCHEMBL3310419 | 0.74 | CA2 (0.41) | CA1CA12CA2CA14CA9 | |
| SCHEMBL20646495 | 0.72 | CA12 (0.63) | CA1PPARACA12CA2CA14 | |
| SCHEMBL22854252 | 0.72 | CA1 (0.48) | CA1PPARACA12CA2CA14 | |
| SCHEMBL41949 | 0.70 | — | — | |
| SCHEMBL3789486 | 0.70 | CA1 (0.83) | CA1PPARACA12CA2CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4234552-A2 | 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF | Raze Therapeutics, Inc. (US) | 2023-08-30 | — | — | EP | disclosed |