Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAG | P20916 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | MLX | Q9UH92 | 1/20 | 0.36 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.36 |
| ▸ | IGF2R | P11717 | 1/20 | 0.35 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.35 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.35 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16311706 | 1.00 | MAG (0.41) | MAGALDH1A1THRBNOD2XIAP | |
| SCHEMBL16311687 | 1.00 | MAG (0.41) | MAGALDH1A1THRBNOD2XIAP | |
| SCHEMBL16311637 | 1.00 | MAG (0.41) | MAGALDH1A1THRBNOD2XIAP | |
| SCHEMBL16311640 | 1.00 | MAG (0.41) | MAGALDH1A1THRBNOD2XIAP | |
| SCHEMBL16311691 | 0.99 | MAG (0.41) | MAGALDH1A1THRBNOD2XIAP | |
| SCHEMBL16311642 | 0.98 | MAG (0.40) | MAGALDH1A1THRBNOD2XIAP | |
| SCHEMBL16311685 | 0.97 | MAG (0.41) | MAGALDH1A1THRBNOD2XIAP | |
| SCHEMBL16311693 | 0.97 | MAG (0.41) | MAGALDH1A1THRBNOD2XIAP | |
| SCHEMBL16311638 | 0.96 | MAG (0.39) | MAGALDH1A1THRBNOD2XIAP | |
| SCHEMBL16311675 | 0.96 | MAG (0.41) | MAGALDH1A1THRBNOD2IGF2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120094933-A1 | DERIVATIVES OF APF AND METHODS OF USE | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120094933-A1 | DERIVATIVES OF APF AND METHODS OF USE | APLNR, ETF1, VIP | MAG 328/4885ALDH1A1 1595/4885THRB 4813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.