Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | CSF1R | P07333 | 3/20 | 0.50 |
| ▸ | KIT | P10721 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.49 |
| ▸ | FLT1 | P17948 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24594026 | 0.83 | CYP2C19 (0.56) | NPC1RAB9AKMT2ACYP2C19CSF1R | |
| SCHEMBL2308761 | 0.81 | NPC1 (0.68) | NPC1RAB9AKMT2AMAPTHDAC1 | |
| SCHEMBL21377439 | 0.81 | CSF1R (0.53) | CYP2C19CSF1RKITCYP3A4LCK | |
| SCHEMBL1885108 | 0.80 | CSF1R (0.81) | CYP2C19CSF1RKITCYP3A4LCK | |
| SCHEMBL28647869 | 0.80 | CYP2C19 (0.48) | CYP2C19CSF1RKITLCKPGR | |
| SCHEMBL2599920 | 0.80 | NPC1 (0.52) | NPC1RAB9AKMT2ACYP2C19CSF1R | |
| SCHEMBL21377437 | 0.80 | CSF1R (0.53) | CYP2C19CSF1RKITCYP3A4LCK | |
| SCHEMBL929327 | 0.80 | TRPV4 (0.52) | KMT2APTGS2MAPTTP53 | |
| SCHEMBL30170521 | 0.79 | CYP2C19 (0.48) | NPC1RAB9AKMT2ACYP2C19CSF1R | |
| SCHEMBL24768087 | 0.79 | CYP2C19 (0.48) | NPC1RAB9AKMT2ACYP2C19CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11767296-B2 | Heteroaryl compounds as kinase inhibitor | FUJIAN HAIXI PHARMACEUTICALS CO., LTD (CN) | 2023-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11767296-B2 | Heteroaryl compounds as kinase inhibitor | RET, ERBB2, ABL1 | NPC1 3660/4885RAB9A 863/4885KMT2A 842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.