SCHEMBL26327160

SCHEMBL26327160

CC(C)(C)[Si](C)(C)O[C@@H]1[C@@H](CO)C[C@@H](N)[C@@H]1O[Si](C)(C)C(C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SI P14410 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6952153 0.77 PPM1D (0.31)
SCHEMBL7622036 0.77 PPM1D (0.31)
SCHEMBL6941367 0.77 PPM1D (0.31)
SCHEMBL17119884 0.75
SCHEMBL783733 0.73 PPM1D (0.31)
SCHEMBL12037002 0.73 PPM1D (0.32)
SCHEMBL783732 0.73 PPM1D (0.31)
SCHEMBL21057093 0.73
SCHEMBL18675854 0.71
SCHEMBL17269112 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111511754-B 2'3' cyclic dinucleotides with phosphonate bonds of activated STING adaptor protein 捷克共和国有机化学与生物化学研究所 2023-09-12 CN disclosed
CN-111511754-A 2'3' cyclic dinucleotides with phosphonate linkages that activate STING transducins 捷克共和国有机化学与生物化学研究所 2020-08-07 CN disclosed