SCHEMBL6952153

SCHEMBL6952153

CC(C)(C)[Si](C)(C)O[C@H]1C2CC2C[C@H]1CO

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PPM1D O15297 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6941367 1.00 PPM1D (0.31) PPM1D
SCHEMBL7622036 1.00 PPM1D (0.31) PPM1D
SCHEMBL17269110 0.77
SCHEMBL18683777 0.77
SCHEMBL17269112 0.77
SCHEMBL18675854 0.77
SCHEMBL17269154 0.77
SCHEMBL26327160 0.77 SI (0.35)
SCHEMBL23128597 0.76
SCHEMBL17119884 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1235832-B1 VITAMIN D PRESCURSORS, METHOD AND INTERMEDIATES THERAMEX (MC) 2003-11-19 EP disclosed
EP-1106618-A1 Precursors of the A-ring of vitamin D, and method and intermediates for the preparation thereof LABORATOIRE THERAMEX (MC) 2001-06-13 EP disclosed
US-6191292-B1 ENZYMATIC ESTERIFICATION OF A DIOL, E.G., METHYL-3-ACETOXY-5-HYDROXY-CYCLOHEXANECARBOXYLATE BY A LIPASE AND VINYL ALKANOATE OR AN ACID ANHYDRIDE; CYCLIZATION TO A BICYCLIC(3.1.0)HEXANE DERIVATIVE LABORATOIRE THERAMEX (MC) 2001-02-20 US disclosed