SCHEMBL26327341

SCHEMBL26327341

CC(C)(C)C(=O)OCSP1(=O)OC[C@H]2C[C@@H](n3cnc4c(N)ncnc43)C(F)[C@H]2OP(=O)(SCOC(=O)C(C)(C)C)OC[C@H]2O[C@@H](n3cnc4c(=O)[nH]c(N)nc43)[C@@H](F)C2O1

nearest known ligand 0.75

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ STING1 Q86WV6 20/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24453576 1.00 STING1 (0.75) STING1
SCHEMBL24453577 1.00 STING1 (0.75) STING1
SCHEMBL24453485 1.00 STING1 (0.75) STING1
SCHEMBL26327142 0.95 STING1 (0.74) STING1
SCHEMBL17860527 0.94 STING1 (0.85) STING1
SCHEMBL24453486 0.93 STING1 (0.87) STING1
SCHEMBL26327323 0.93 STING1 (0.87) STING1
SCHEMBL24453624 0.93 STING1 (0.87) STING1
SCHEMBL24453625 0.93 STING1 (0.87) STING1
SCHEMBL21133002 0.92 STING1 (0.81) STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11766447-B2 3′3′-cyclic dinucleotide analogue comprising a cyclopentanyl modified nucleotide as sting modulator INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. (CZ) 2023-09-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11766447-B2 3′3′-cyclic dinucleotide analogue comprising a cyclopentanyl modified nucleotide as sting modulator STING1, MAVS, CGAS STING1 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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