Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20375692 | 0.96 | CYP2D6 (0.36) | CYP2D6HRH3 | |
| SCHEMBL22918414 | 0.92 | CYP2D6 (0.34) | CYP2D6HRH3 | |
| SCHEMBL24735238 | 0.91 | CYP2D6 (0.30) | CYP2D6 | |
| SCHEMBL22645245 | 0.88 | CYP2D6 (0.36) | CYP2D6HRH3 | |
| SCHEMBL20375693 | 0.87 | CYP2D6 (0.33) | CYP2D6HRH3 | |
| SCHEMBL10111448 | 0.85 | CYP2D6 (0.42) | CYP2D6HRH3 | |
| SCHEMBL22645192 | 0.82 | HRH3 (0.30) | HRH3 | |
| SCHEMBL23551954 | 0.82 | HRH3 (0.33) | HRH3 | |
| SCHEMBL10111441 | 0.79 | CYP2D6 (0.39) | CYP2D6HRH3 | |
| SCHEMBL24827975 | 0.79 | HRH3 (0.30) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11767330-B2 | Citrate salt, pharmaceutical compositions, and methods of making and using the same | FOGHORN THERAPEUTICS INC. (US) | 2023-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11767330-B2 | Citrate salt, pharmaceutical compositions, and methods of making and using the same | CS, SMARCC2, SMARCC1 | CYP2D6 2726/4885HRH3 2752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.