Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 18/20 | 0.52 |
| ▸ | CRBN | Q96SW2 | 18/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21965731 | 0.84 | CRBN (0.72) | DDB1CRBN | |
| SCHEMBL26328129 | 0.80 | CRBN (0.55) | DDB1CRBN | |
| SCHEMBL25834467 | 0.80 | DDB1 (0.75) | DDB1CRBN | |
| SCHEMBL29116583 | 0.76 | DDB1 (0.53) | DDB1CRBN | |
| SCHEMBL25847911 | 0.74 | DDB1 (0.43) | DDB1CRBN | |
| SCHEMBL19606506 | 0.74 | DDB1 (0.38) | DDB1CRBN | |
| SCHEMBL26328771 | 0.73 | CRBN (0.50) | DDB1CRBN | |
| SCHEMBL26500892 | 0.71 | CRBN (0.71) | DDB1CRBN | |
| SCHEMBL21965830 | 0.69 | CRBN (0.73) | DDB1CRBN | |
| SCHEMBL21965363 | 0.69 | CRBN (1.00) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230279023-A1 | N/O-Linked Degrons and Degronimers for Protein Degradation | C4 THERAPEUTICS, INC. (US) | 2023-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230279023-A1 | N/O-Linked Degrons and Degronimers for Protein Degradation | CRBN, CBL, STUB1 | DDB1 319/4885CRBN 1/4885HDAC8 3091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.