Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | YTHDF2 | Q9Y5A9 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11243798 | 0.84 | KMT2A (0.54) | MEN1KMT2ASMN1; SMN2HTTTP53 | |
| SCHEMBL2070591 | 0.82 | MEN1 (0.56) | MEN1KMT2ASMN1; SMN2HTTTP53 | |
| Methane SCHEMBL11401135 | 0.80 | MEN1 (0.54) | MEN1KMT2ASMN1; SMN2HTTTP53 | |
| SCHEMBL2625570 | 0.79 | SMN1; SMN2 (0.65) | MEN1KMT2ASMN1; SMN2HTTTP53 | |
| SCHEMBL16480329 | 0.79 | SMN1; SMN2 (0.59) | MEN1KMT2ASMN1; SMN2HTTTP53 | |
| SCHEMBL22521954 | 0.76 | SMN1; SMN2 (0.64) | MEN1KMT2ASMN1; SMN2HTTTP53 | |
| SCHEMBL13456857 | 0.75 | CYP3A4 (0.59) | MEN1KMT2ASMN1; SMN2HTTTP53 | |
| SCHEMBL220198 | 0.74 | KMT2A (0.51) | MEN1KMT2ASMN1; SMN2HTTTP53 | |
| SCHEMBL5251305 | 0.73 | MEN1 (0.77) | MEN1KMT2ASMN1; SMN2HTTTP53 | |
| SCHEMBL5307016 | 0.73 | MEN1 (1.00) | MEN1KMT2ASMN1; SMN2HTTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591336-B | 5-hydroxy-3-methylpyrido [2,3-d ] pyrimidine compound and preparation and application thereof | 沈阳药科大学 | 2023-07-25 | — | — | CN | disclosed |
| CN-114591336-A | 5-hydroxy-3-methylpyrido [2,3-d ] pyrimidine compound and preparation and application thereof | 沈阳药科大学 | 2022-06-07 | — | — | CN | disclosed |
| US-9809713-B2 | Photoactivatable crosslinker compositions for surface modification | INNOVATION SURFACE TECHNOLOGIES, INC. (US) | 2017-11-07 | — | — | US | disclosed |
| US-20160040121-A1 | THERMALLY RESPONSIVE CELL CULTURE SURFACES | INNOVATIVE SURFACE TECHNOLOGIES INC (US) | 2016-02-11 | — | — | US | disclosed |
| WO-2015188060-A1 | FLUOROSULFONYL sEH INHIBITORS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2015-12-10 | — | — | WO | disclosed |
| US-9116144-B2 | Methods for preparing thermally responsive cell culture surfaces | INNOVATIVE SURFACE TECHNOLOGIES, INC. (US) | 2015-08-25 | — | — | US | disclosed |
| US-8815259-B2 | Drug eluting superhydrophobic coatings | INNOVATIVE SURFACE TECHNOLOGIES, INC. (US) | 2014-08-26 | — | — | US | disclosed |
| US-20140205849-A1 | BRUSH POLYMER COATING BY IN SITU POLYMERIZATION FROM PHOTOREACTIVE SURFACE | INNOVATIVE SURFACE TECHNOLOGIES, INC. (US) | 2014-07-24 | — | — | US | disclosed |
| US-20140199468-A1 | NANOFIBERS CONTAINING LATENT REACTIVE GROUPS | INNOVATIVE SURFACE TECHNOLOGIES, INC. (US) | 2014-07-17 | — | — | US | disclosed |
| US-8779206-B2 | Photochemical crosslinkers for polymer coatings and substrate tie-layer | INNOVATIVE SURFACE TECHNOLOGIES, LLC (US) | 2014-07-15 | — | — | US | disclosed |
| US-8709809-B2 | Nanofibers containing latent reactive groups | INNOVATIVE SURFACE TECHNOLOGIES, INC. (US) | 2014-04-29 | — | — | US | disclosed |
| US-20130303759-A1 | PHOTOCHEMICAL CROSSLINKERS FOR POLYMER COATINGS AND SUBSTRATE TIE-LAYER | INNOVATIVE SURFACE TECHNOLOGIES LLC (US) | 2013-11-14 | — | — | US | disclosed |
| EP-2318377-B1 | PYRIMIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | GENENTECH INC (US) | 2013-08-21 | — | — | EP | disclosed |
| US-8496857-B2 | Nanotextured surfaces | INNOVATIVE SURFACE TECHNOLOGIES, INC. (US) | 2013-07-30 | — | — | US | disclosed |
| US-8487137-B2 | Photochemical crosslinkers for polymer coatings and substrate tie-layer | INNOVATIVE SURFACE TECHNOLOGIES, LLC (US) | 2013-07-16 | — | — | US | disclosed |
| US-20130171331-A1 | Stimuli Responsive Nanofibers | NAQVI TAHMINA (US) | 2013-07-04 | — | — | US | disclosed |
| US-8163763-B2 | Pyrimidine compounds, compositions and methods of use | GENENTECH, INC. (US) | 2012-04-24 | — | — | US | disclosed |
| EP-1891022-B1 | PHOTOCHEMICAL CROSSLINKERS FOR POLYMER COATINGS AND SUBSTRATE TIE-LAYER | INNOVATIVE SURFACE TECHNOLOGIES INC (US) | 2012-04-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130303759-A1 | PHOTOCHEMICAL CROSSLINKERS FOR POLYMER COATINGS AND SUBSTRATE TIE-LAYER | TIE1, LIG4, LIG3 | MEN1 583/4885KMT2A 932/4885SMN1; SMN2 4752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.