SCHEMBL220198

SCHEMBL220198

Cn1c(=O)cc(Cl)[nH]c1=O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.51
MEN1 O00255 3/20 0.51
YTHDF2 Q9Y5A9 1/20 0.50
LMNA P02545 4/20 0.47
PABPC1 P11940 1/20 0.44
SMN1; SMN2 Q16637 4/20 0.44
HTT P42858 1/20 0.44
GAA P10253 2/20 0.43
TP53 P04637 1/20 0.42
KDM4C Q9H3R0 1/20 0.40
ALDH1A1 P00352 2/20 0.39
NR1I2 O75469 1/20 0.39
HPGD P15428 1/20 0.39
AHR P35869 1/20 0.39
BRCA1 P38398 2/20 0.38
ALOX15 P16050 1/20 0.38
TSHR P16473 1/20 0.38
RXFP1 Q9HBX9 1/20 0.38
PGR P06401 1/20 0.37
CASP1 P29466 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL30517206 0.98 KMT2A (0.50) KMT2AMEN1YTHDF2LMNAPABPC1
SCHEMBL2632820 0.74 YTHDF2 (0.52) KMT2AMEN1YTHDF2LMNAPABPC1
SCHEMBL2632919 0.74 MEN1 (0.57) KMT2AMEN1YTHDF2LMNAPABPC1
SCHEMBL3297433 0.74 KMT2A (0.54) KMT2AMEN1LMNASMN1; SMN2GAA
SCHEMBL15038565 0.73 KMT2A (0.44) KMT2AMEN1LMNASMN1; SMN2GAA
SCHEMBL10281144 0.73 YTHDF2 (0.50) KMT2AMEN1YTHDF2LMNAPABPC1
SCHEMBL12432833 0.73 YTHDF2 (0.50) KMT2AMEN1YTHDF2LMNAPABPC1
SCHEMBL1947779 0.73 YTHDF2 (0.50) KMT2AMEN1YTHDF2LMNAPABPC1
SCHEMBL10855053 0.72 CYP3A4 (0.50) KMT2ASMN1; SMN2GAAALDH1A1PGR
SCHEMBL220200 0.72 KMT2A (0.57) KMT2AMEN1LMNASMN1; SMN2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 537 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036725-A Method for preparing denitrification flavin second generation 山东丰金制药有限公司 2026-05-15 CN claimed
EP-4560315-A2 HYBRIDIZING ALL-LNA OLIGONUCLEOTIDES F. Hoffmann-La Roche AG (CH) 2025-05-28 EP claimed
EP-3980554-B1 HYBRIDIZING ALL-LNA OLIGONUCLEOTIDES HOFFMANN LA ROCHE (CH) 2025-03-26 EP claimed
CN-118063396-A Preparation method of 6-chloro-3-methyl uracil 黑龙江立科新材料有限公司 2024-05-24 CN claimed
CN-112939937-B Synthesis process of trelagliptin succinate 合肥工业大学 2023-09-22 CN claimed
CN-116143748-A Preparation method of trelagliptin succinate related substances 浙江燎原药业有限公司 2023-05-23 CN claimed
CN-115536597-A Preparation method of high-purity alogliptin benzoate intermediate 山东新华制药股份有限公司 2022-12-30 CN claimed
US-20220195497-A1 HYBRIDIZING all-LNA OLIGONUCLEOTIDES ROCHE DIAGNOSTICS OPERATIONS, INC. 2022-06-23 US claimed
CN-111693627-B Detection method and application of 6-chloro-3-methyl uracil and related substances thereof 山西振东制药股份有限公司 2022-05-13 CN claimed
EP-3980554-A1 HYBRIDIZING ALL-LNA OLIGONUCLEOTIDES F. Hoffmann-La Roche AG (CH) 2022-04-13 EP claimed
CN-105968091-A Method for preparing drug Alogliptin for treating diabetes type II 青岛辰达生物科技有限公司 2016-09-28 CN claimed
CN-104151291-B A kind of preparation method of SYR-322 polymorph crystals JIANGSU DEYUAN PHARMACEUTICAL CO., LTD. (CN) 2016-01-20 CN claimed
CN-104961726-A Preparation method of trelagliptin ZHEJIANG YONGNING PHARMA CO LTD 2015-10-07 CN claimed
WO-2015092739-A1 PROCESS FOR PREPARATION OF ALOGLIPTIN Mylan Laboratories Ltd. (IN) 2015-06-25 WO claimed
WO-2015092807-A1 A NOVEL PROCESS FOR PREPARATION OF ALOGLIPTIN BENZOATE HARMAN FINOCHEM LIMITED (IN) 2015-06-25 WO claimed
CN-104193726-A Synthesis method of alogliptin benzoate JIANGSU DEYUAN PHARMACEUTICAL CO LTD 2014-12-10 CN claimed
CN-104151253-A Synthesis method of Alogliptin intermediate SICHUAN TONGSHENG BIOTECHNOLOGY CO LTD 2014-11-19 CN claimed
CN-104151291-A Preparation method for benzoic acid alogliptin polycrystalline type crystal JIANGSU DEYUAN PHARMACEUTICAL CO LTD 2014-11-19 CN claimed
CN-103819450-A Novel method for preparing alogliptin benzoate ZHEJIANG YONGNING PHARMA CO LTD 2014-05-28 CN claimed
CN-103012287-A Preparation method of 6-chlorine-3-methyl uracil HEALTANG BIOTECH CO LTD 2013-04-03 CN claimed