Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19538628 | 0.82 | PTPN1 (0.37) | ALDH1A1PIK3CDMMP8 | |
| SCHEMBL21164763 | 0.80 | ALDH1A1 (0.49) | ALDH1A1 | |
| SCHEMBL21164616 | 0.79 | MAPT (0.40) | ALDH1A1PIK3CDDPP4 | |
| SCHEMBL23916964 | 0.78 | ALDH1A1 (0.39) | ALDH1A1PIK3CDMMP8 | |
| SCHEMBL12308386 | 0.76 | CYP1A2 (0.37) | ALDH1A1PIK3CDMMP8 | |
| SCHEMBL12308387 | 0.73 | PIK3CD (0.40) | ALDH1A1PIK3CDMMP8 | |
| SCHEMBL25091539 | 0.73 | PIK3CD (0.32) | PIK3CDDPP4 | |
| SCHEMBL12308384 | 0.73 | ALDH1A1 (0.40) | ALDH1A1PIK3CDMMP8 | |
| SCHEMBL21164617 | 0.73 | MEN1 (0.37) | ALDH1A1DPP4 | |
| SCHEMBL23168321 | 0.73 | CYP2C19 (0.41) | ALDH1A1PIK3CDMMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230233692-A1 | COMPOUNDS FOR TARGETED DEGRADATION OF RET | C4 THERAPEUTICS, INC. (US) | 2023-07-27 | — | — | US | disclosed |
| US-20230233692-A1 | COMPOUNDS FOR TARGETED DEGRADATION OF RET | C4 THERAPEUTICS, INC. (US) | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230233692-A1 | COMPOUNDS FOR TARGETED DEGRADATION OF RET | RET, HRAS, RBX1 | ALDH1A1 3400/4885PIK3CD 2317/4885MMP8 3408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.