SCHEMBL26329757

SCHEMBL26329757

c1ccc(-n2c3ccc(-n4c5ccccc5c5ccc6c7ccccc7n(-c7ccccc7)c6c54)cc3c3ncncc32)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
ATM Q13315 1/20 0.44
CYP1A2 P05177 9/20 0.35
USP2 O75604 7/20 0.35
CYP2C19 P33261 6/20 0.35
CYP3A4 P08684 6/20 0.35
TSHR P16473 5/20 0.35
KMT2A Q03164 4/20 0.35
MEN1 O00255 3/20 0.35
CASP1 P29466 2/20 0.35
CASP7 P55210 2/20 0.35
HBB P68871 1/20 0.35
CYP2C9 P11712 6/20 0.34
MAPK1 P28482 4/20 0.34
HSD17B10 Q99714 6/20 0.33
ALDH1A1 P00352 6/20 0.33
HPGD P15428 2/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26329827 0.90 KDM4E (0.46) KDM4EL3MBTL1ATMCYP1A2USP2
SCHEMBL26329749 0.84 KDM4E (0.47) KDM4EL3MBTL1ATMCYP1A2CYP2C19
SCHEMBL26329758 0.83 KDM4E (0.41) KDM4EL3MBTL1ATMCYP1A2USP2
SCHEMBL29457594 0.83 L3MBTL1 (0.55) KDM4EL3MBTL1ATMCYP1A2USP2
SCHEMBL22761946 0.83 L3MBTL1 (0.55) KDM4EL3MBTL1ATMCYP1A2USP2
SCHEMBL16304718 0.82 L3MBTL1 (0.38) KDM4EL3MBTL1ATMCYP1A2USP2
SCHEMBL16304690 0.82 KDM4E (0.36) KDM4EL3MBTL1ATMCYP1A2USP2
SCHEMBL24531866 0.81 L3MBTL1 (0.62) KDM4EL3MBTL1ATMTSHRKMT2A
SCHEMBL10206018 0.81 L3MBTL1 (0.62) KDM4EL3MBTL1ATMTSHRKMT2A
SCHEMBL10029945 0.81 L3MBTL1 (0.62) KDM4EL3MBTL1ATMTSHRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11723269-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-08 US disclosed
US-11723269-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11723269-B2 Organic electroluminescent materials and devices PUF60, CD99, DDT KDM4E 3163/4885L3MBTL1 1292/4885ATM 3362/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.