SCHEMBL26329800

SCHEMBL26329800

c1ccc(-n2c3ccccc3c3cc4c5ccccc5n(-c5ccc6c(c5)c5cncnc5n6-c5ccccc5)c4cc32)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.45
ATM Q13315 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
CYP1A2 P05177 12/20 0.40
USP2 O75604 10/20 0.40
CYP3A4 P08684 10/20 0.40
CYP2C19 P33261 9/20 0.40
TSHR P16473 5/20 0.40
MEN1 O00255 4/20 0.40
KMT2A Q03164 4/20 0.40
CASP1 P29466 3/20 0.40
CASP7 P55210 3/20 0.40
HBB P68871 1/20 0.40
CYP2C9 P11712 9/20 0.39
ALDH1A1 P00352 5/20 0.39
HSD17B10 Q99714 5/20 0.39
MAPK1 P28482 4/20 0.38
DDB1 Q16531 1/20 0.36
CRBN Q96SW2 1/20 0.36
CYP2D6 P10635 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26329875 0.90 KDM4E (0.41) KDM4EATML3MBTL1CYP1A2USP2
SCHEMBL26478049 0.90 CYP1A2 (0.44) KDM4EATML3MBTL1CYP1A2USP2
SCHEMBL26329758 0.89 KDM4E (0.41) KDM4EATML3MBTL1CYP1A2USP2
SCHEMBL12396569 0.87 KDM4E (0.55) KDM4EATML3MBTL1CYP1A2USP2
SCHEMBL26329989 0.86 KDM4E (0.39) KDM4EATML3MBTL1CYP1A2USP2
SCHEMBL26329788 0.83 KDM4E (0.49) KDM4EATML3MBTL1CYP2C19TSHR
SCHEMBL21398006 0.82 CYP1A2 (0.40) KDM4EATML3MBTL1CYP1A2USP2
SCHEMBL18253998 0.82 L3MBTL1 (0.67) KDM4EATML3MBTL1TSHRMEN1
SCHEMBL17245437 0.82 L3MBTL1 (0.67) KDM4EATML3MBTL1TSHRMEN1
SCHEMBL26809766 0.82 L3MBTL1 (0.67) KDM4EATML3MBTL1TSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11723269-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-08 US disclosed
US-11723269-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11723269-B2 Organic electroluminescent materials and devices PUF60, CD99, DDT KDM4E 3163/4885ATM 3362/4885L3MBTL1 1292/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.