Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.44 |
| ▸ | GAK | O14976 | 3/20 | 0.43 |
| ▸ | TTK | P33981 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.41 |
| ▸ | SYK | P43405 | 2/20 | 0.41 |
| ▸ | ATR | Q13535 | 2/20 | 0.40 |
| ▸ | CCNC | P24863 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25849444 | 0.86 | KMT2A (0.47) | LRRK2GAK | |
| SCHEMBL26317979 | 0.85 | IDH1 (0.41) | LRRK2TTKPDE10ASYKCCNC | |
| SCHEMBL24005893 | 0.83 | CCNC (0.55) | PDE10ACCNCCDK8 | |
| SCHEMBL26081274 | 0.82 | LRRK2 (0.38) | LRRK2SYKATRIDH1 | |
| SCHEMBL26318318 | 0.82 | DOT1L (0.43) | — | |
| SCHEMBL24532414 | 0.81 | LMNA (0.45) | LRRK2SYKATRIDH1 | |
| SCHEMBL24532297 | 0.81 | LMNA (0.45) | LRRK2SYKATRIDH1 | |
| SCHEMBL29681601 | 0.81 | LMNA (0.45) | LRRK2SYKATRIDH1 | |
| SCHEMBL29680917 | 0.81 | LMNA (0.45) | LRRK2SYKATRIDH1 | |
| SCHEMBL24532305 | 0.81 | LMNA (0.45) | LRRK2SYKATRIDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295114-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295114-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | LRRK2 507/4885GAK 499/4885TTK 1031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.