Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 19/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.50 |
| ▸ | GABRP | O00591 | 1/20 | 0.49 |
| ▸ | GABRD | O14764 | 1/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.49 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.49 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.49 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.49 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.49 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.49 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.49 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.49 |
| ▸ | GABRE | P78334 | 1/20 | 0.49 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.49 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.49 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.49 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7034839 | 0.94 | AR (0.57) | ARHDAC1NR3C1GABRPGABRD | |
| SCHEMBL1715562 | 0.93 | AR (0.64) | ARHDAC1NR3C1 | |
| SCHEMBL30184864 | 0.93 | AR (0.64) | ARHDAC1NR3C1 | |
| SCHEMBL7031925 | 0.89 | AR (0.66) | AR | |
| SCHEMBL20003455 | 0.83 | AR (0.52) | ARHDAC1NR3C1 | |
| SCHEMBL1715104 | 0.82 | AR (0.69) | ARHDAC1NR3C1GABRPGABRD | |
| SCHEMBL30184903 | 0.82 | AR (0.69) | ARHDAC1NR3C1GABRPGABRD | |
| SCHEMBL30184878 | 0.79 | AR (0.69) | ARHDAC1NR3C1 | |
| SCHEMBL1716007 | 0.79 | AR (0.69) | ARHDAC1NR3C1 | |
| SCHEMBL16564502 | 0.78 | AR (0.68) | ARNR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2444085-A1 | Diarylhydantoin compounds as androgen receptor antagonists for treatment of cancer | The Regents of The University of California (US) | 2012-04-25 | — | — | EP | disclosed |